HitPredict

Interactor 1: CLGN (O14967)
Calmegin
Gene: CLGN

Interactor 2: SORL (Q92673)
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)
Gene: SORL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 610 Hs			1 2214
+	Hs
		698967 CALX_HUMAN (29-610): 0: 729: 56.85		SORL_HUMAN (1-2214): 0: 1914: 100.00
+	Hs
		170932 CLGN_HUMAN (1-610): 0: 804: 100.00		SORT_HUMAN (60-756): 1.92e-179: 571: 28.88
+	Hs
		699038 CALX_HUMAN (29-610): 0: 729: 56.85		SORT_HUMAN (60-756): 1.92e-179: 571: 28.88
+	Hs
		170584 CLGN_HUMAN (1-610): 0: 804: 100.00		LRP6_HUMAN (1445-1549): 6.83e-11: 70.1: 36.94
+	Hs
		170578 CLGN_HUMAN (1-610): 0: 804: 100.00		LRP5_HUMAN (1445-1549): 8.72e-11: 69.7: 37.27
+	Hs
		376480 CALX_HUMAN (29-610): 0: 729: 56.85		LDLR_HUMAN (1077-1278): 2.78e-29: 129: 34.48
+	Hs
		698587 CALX_HUMAN (29-610): 0: 729: 56.85		VLDLR_HUMAN (1457-1575): 6.52e-21: 102: 28.57
+	Hs
		698604 CALX_HUMAN (29-610): 0: 729: 56.85		LRP1_HUMAN (1155-1311): 3.67e-09: 64.6: 21.82
+	Hs
		697857 CALR_HUMAN (60-456): 2.92e-129: 387: 36.00		LRP1_HUMAN (1155-1311): 3.67e-09: 64.6: 21.82