HitPredict

Interactor 1: CETN3 (O15182)
Centrin-3
Gene: CETN3

Interactor 2: UBP49 (Q70CQ1)
Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49)
Gene: USP49

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	33961781, 35367823, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 167 Hs			1 688
+	Hs
		171169 CETN3_HUMAN (1-167): 8.98e-85: 248: 100.00		UBP44_HUMAN (1-682): 0: 543: 58.36
+	Hs
		1016728 CETN1_HUMAN (13-163): 2.24e-44: 145: 58.94		UBP49_HUMAN (1-688): 0: 584: 100.00
+	Hs
		781563 CETN2_HUMAN (13-163): 1.24e-42: 141: 57.62		UBP49_HUMAN (1-688): 0: 584: 100.00
+	Hs
		1016742 CETN1_HUMAN (13-163): 2.24e-44: 145: 58.94		UBP44_HUMAN (1-682): 0: 543: 58.36
+	Hs
		781595 CETN2_HUMAN (13-163): 1.24e-42: 141: 57.62		UBP44_HUMAN (1-682): 0: 543: 58.36
+	Mm
		1207912 CETN2_MOUSE (13-163): 5.55e-43: 142: 57.62		UBP44_MOUSE (1-682): 2.63e-177: 524: 54.52
+	Sc
		416794 CDC31_YEAST (21-164): 3.21e-46: 150: 61.81		UBP8_YEAST (249-660): 5.53e-89: 287: 27.58
+	Sc
		420306 CALM_YEAST (22-164): 1.86e-20: 84: 36.36		UBP8_YEAST (249-660): 5.53e-89: 287: 27.58
+	Sc
		420289 CALM_YEAST (22-164): 1.86e-20: 84: 36.36		UBP9_YEAST (397-681): 5.18e-19: 93.6: 27.76