Interactor 1: EPHB6 (O15197)
Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)
Gene: EPHB6
Interactor 2: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 21737611 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | EphA2_TM~PK_Tyr_Ser-Thr, Ephrin_lbd~Ephrin_lbd, Ephrin_lbd~fn3, fn3~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SAM_1, SAM_1~SAM_2 |
Common GO terms | GO:0005005 - transmembrane-ephrin receptor activity GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0007411 - axon guidance GO:0030425 - dendrite and 1 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024