Protein: KCMF1
E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (FGF-induced in gastric cancer) (Potassium channel modulatory factor) (PCMF) (ZZ-type zinc finger-containing protein 1)

Gene: KCMF1
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q9P0J7

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005770 - late endosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1212868

UBR4
E3 ubiquitin-protein ligase UBR4

7

2

Small-scale

0.742

High

1453776

NPS3A
Protein NipSnap homolog 3A

5

1

Small-scale

0.712

High

1241601

CEP85
Centrosomal protein of 85 kDa

4

4

High-throughput

0.691

High

1446013

SYSM
Serine--tRNA ligase, mitochondrial

5

0

Small-scale

0.682

High

1449843

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

5

0

Small-scale

0.682

High

1453774

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

12

Small-scale

0.647

High

231063

VEGFD
Vascular endothelial growth factor D

3

0

High-throughput

0.638

High

877396

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

3

0

High-throughput

0.638

High

1236112

FSTL4
Follistatin-related protein 4

2

5

High-throughput

0.628

High

407013

A1BG
Alpha-1B-glycoprotein

2

0

High-throughput

0.602

High

1178962

TM266
Transmembrane protein 266

2

0

High-throughput

0.602

High

508745

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

11

Small-scale

0.595

High

1063661

GOGA2
Golgin subfamily A member 2

3

2

High-throughput

0.593

High

1453785

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

3

1

Small-scale

0.593

High

884408

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

20

Small-scale

0.586

High

60631

TESP1
Protein TESPA1

2

0

High-throughput

0.585

High

1204662

TFDP3
Transcription factor Dp family member 3

2

0

High-throughput

0.585

High

935211

TERA
Transitional endoplasmic reticulum ATPase

2

1

High-throughput

0.584

High

1114501

CUL3
Cullin-3

2

7

High-throughput

0.584

High

1233268

ELP2
Elongator complex protein 2

2

0

High-throughput

0.576

High

538033

HSP7C
Heat shock cognate 71 kDa protein

2

2

High-throughput

0.571

High

415907

HSPB1
Heat shock protein beta-1

1

6

High-throughput

0.541

High

66524

RASFA
Ras association domain-containing protein 10

1

1

High-throughput

0.536

High

286733

STX11
Syntaxin-11

1

3

High-throughput

0.536

High

296895

RASF9
Ras association domain-containing protein 9

1

1

High-throughput

0.536

High

503672

TFPT
TCF3 fusion partner

1

1

High-throughput

0.536

High

540098

BCR
Breakpoint cluster region protein

1

3

High-throughput

0.536

High

659617

CRCM
Colorectal mutant cancer protein

1

5

High-throughput

0.536

High

840899

TEC
Tyrosine-protein kinase Tec

1

7

High-throughput

0.536

High

872826

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.536

High

1116807

RAPSN
43 kDa receptor-associated protein of the synapse

1

4

High-throughput

0.536

High

1329135

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

1

High-throughput

0.536

High

1341067

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

1

High-throughput

0.536

High

1348896

ARRD2
Arrestin domain-containing protein 2

1

5

High-throughput

0.536

High

1382706

EMID1
EMI domain-containing protein 1

1

2

High-throughput

0.536

High

1391816

AURKB
Aurora kinase B

1

2

High-throughput

0.536

High

1410392

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.536

High

1453779

EGFL7
Epidermal growth factor-like protein 7

1

3

High-throughput

0.536

High

1453780

CLC2D
C-type lectin domain family 2 member D

1

3

High-throughput

0.536

High

1453787

EMIL1
EMILIN-1

1

4

High-throughput

0.536

High

506913

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

640625

MK
Midkine

1

0

High-throughput

0.513

High

683760

PTX3
Pentraxin-related protein PTX3

1

0

High-throughput

0.513

High

873376

AL3B2
Aldehyde dehydrogenase family 3 member B2

1

0

High-throughput

0.513

High

1017502

FOXK1
Forkhead box protein K1

1

0

High-throughput

0.513

High

1163947

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.513

High

1210434

LY65C
Lymphocyte antigen 6 complex locus protein G5c

1

0

High-throughput

0.513

High

1272097

MIGA2
Mitoguardin 2

1

0

High-throughput

0.513

High

1308304

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

1381292

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.513

High

1384670

ELMO3
Engulfment and cell motility protein 3

1

0

High-throughput

0.513

High

1401203

O52B2
Olfactory receptor 52B2

1

0

High-throughput

0.513

High

1431615

IL25
Interleukin-25

1

0

High-throughput

0.513

High

1438757

CAN10
Calpain-10

1

0

High-throughput

0.513

High

1453777

MIOX
Inositol oxygenase

1

0

High-throughput

0.513

High

890706

RGS4
Regulator of G-protein signaling 4

1

0

Small-scale

0.505

High

982344

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

Small-scale

0.501

High

1147451

EPHA7
Ephrin type-A receptor 7

1

4

High-throughput

0.500

High

1416930

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.500

High

1289376

ST32C
Serine/threonine-protein kinase 32C

1

2

High-throughput

0.489

High

1398211

PPM1M
Protein phosphatase 1M

1

1

High-throughput

0.489

High

1403460

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

173481

XPO1
Exportin-1

1

7

High-throughput

0.479

High

186085

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

Small-scale

0.479

High

224379

BUB3
Mitotic checkpoint protein BUB3

1

1

High-throughput

0.479

High

243165

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

276351

HMMR
Hyaluronan mediated motility receptor

1

3

High-throughput

0.479

High

291968

WDHD1
WD repeat and HMG-box DNA-binding protein 1

1

2

High-throughput

0.479

High

431264

LA
Lupus La protein

1

1

High-throughput

0.479

High

487834

PARP1
Poly [ADP-ribose] polymerase 1

1

14

High-throughput

0.479

High

560542

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

762061

GRK5
G protein-coupled receptor kinase 5

1

1

High-throughput

0.479

High

775611

NU214
Nuclear pore complex protein Nup214

1

1

Small-scale

0.479

High

879558

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

990995

UBE2B
Ubiquitin-conjugating enzyme E2 B

1

20

Small-scale

0.479

High

1016656

SRSF3
Serine/arginine-rich splicing factor 3

1

3

High-throughput

0.479

High

1031573

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

1033798

PO5F1
POU domain, class 5, transcription factor 1

1

4

High-throughput

0.479

High

1102119

PABP4
Polyadenylate-binding protein 4

1

1

High-throughput

0.479

High

1255878

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.479

High

1290349

SERC5
Serine incorporator 5

1

2

Small-scale

0.479

High

1360954

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.479

High

1368905

RBP56
TATA-binding protein-associated factor 2N

1

2

High-throughput

0.479

High

1369314

EDA
Ectodysplasin-A

1

1

High-throughput

0.479

High

1412038

WDR83
WD repeat domain-containing protein 83

1

1

High-throughput

0.479

High

1434097

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1435386

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1438204

RHOF
Rho-related GTP-binding protein RhoF

1

13

High-throughput

0.479

High

1446981

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

3

High-throughput

0.479

High

1453775

RCC2
Protein RCC2

1

1

High-throughput

0.479

High

1453778

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1453782

KDIS
Kinase D-interacting substrate of 220 kDa

1

9

High-throughput

0.479

High

1453783

CLC4E
C-type lectin domain family 4 member E

1

3

High-throughput

0.479

High

228385

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

376914

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

390790

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

429030

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

459342

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

611999

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

686490

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.458

High

820798

TACT
T-cell surface protein tactile

1

0

High-throughput

0.458

High

842580

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

843061

PCP
Lysosomal Pro-X carboxypeptidase

1

0

Small-scale

0.458

High

868269

SYQ
Glutamine--tRNA ligase

1

0

Small-scale

0.458

High

1039431

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

1210380

NU188
Nucleoporin NUP188

1

0

Small-scale

0.458

High

1218682

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

1286940

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.458

High

1323478

NUP93
Nuclear pore complex protein Nup93

1

0

Small-scale

0.458

High

1338408

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1395725

ZN668
Zinc finger protein 668

1

0

High-throughput

0.458

High

1399009

BROMI
Protein broad-minded

1

0

Small-scale

0.458

High

1418487

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1420118

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.458

High

1433676

FA83D
Protein FAM83D

1

0

High-throughput

0.458

High

990805

1433Z
14-3-3 protein zeta/delta

1

5

Small-scale

0.457

High

157939

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.445

High

331812

MTMR5
Myotubularin-related protein 5

1

1

High-throughput

0.445

High

354790

PAK4
Serine/threonine-protein kinase PAK 4

1

4

High-throughput

0.445

High

1065774

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

3

High-throughput

0.445

High

1289993

LUZP1
Leucine zipper protein 1

1

5

High-throughput

0.445

High

1341038

THOC2
THO complex subunit 2

1

1

High-throughput

0.445

High

1413326

DIDO1
Death-inducer obliterator 1

1

3

High-throughput

0.445

High

1409614

NIPS1
Protein NipSnap homolog 1

1

1

Small-scale

0.437

High

841590

I12R1
Interleukin-12 receptor subunit beta-1

1

0

High-throughput

0.426

High

1195318

TB10B
TBC1 domain family member 10B

1

0

High-throughput

0.426

High

1199726

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

1390984

THOC1
THO complex subunit 1

1

0

High-throughput

0.426

High

1437724

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.426

High

1453781

S39AA
Zinc transporter ZIP10

1

0

High-throughput

0.426

High

1453784

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.426

High

1453788

MORC2
ATPase MORC2

1

0

High-throughput

0.426

High

260556

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.407

High

284723

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

2

High-throughput

0.407

High

288205

CLC3A
C-type lectin domain family 3 member A

1

3

High-throughput

0.407

High

1365862

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

2

High-throughput

0.407

High

1409719

MICU1
Calcium uptake protein 1, mitochondrial

1

1

High-throughput

0.407

High

1220002

CST9
Cystatin-9

3

0

High-throughput

0.347

High

1439551

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

3

0

High-throughput

0.347

High

1048741

SSBP
Single-stranded DNA-binding protein, mitochondrial

2

0

Small-scale

0.318

High

139423

VMA5A
von Willebrand factor A domain-containing protein 5A

1

0

High-throughput

0.279

Low

289825

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

1209011

PPR29
Protein phosphatase 1 regulatory subunit 29

1

0

High-throughput

0.279

Low

1435928

RDD1
Required for drug-induced death protein 1

1

0

High-throughput

0.279

Low

192515

INSI1
Insulin-induced gene 1 protein

1

0

Small-scale

0.249

Low

352575

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

542257

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.249

Low

1083448

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

0

High-throughput

0.249

Low

1256749

NKAP1
Uncharacterized protein NKAPD1

1

0

High-throughput

0.249

Low

1333663

PGLT1
Protein O-glucosyltransferase 1

1

0

High-throughput

0.249

Low

1436784

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.249

Low

183761

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.232

Low

516933

CB27B
Putative uncharacterized protein CDRT15P3

1

0

High-throughput

0.232

Low

1131493

MBTP1
Membrane-bound transcription factor site-1 protease

1

0

High-throughput

0.232

Low

1177112

INF2
Inverted formin-2

1

0

High-throughput

0.232

Low

1357919

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.232

Low

1380551

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.232

Low

1453765

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.232

Low

1453786

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025