HitPredict

Interactor 1: GP182 (O15218)
G-protein coupled receptor 182
Gene: GPR182

Interactor 2: BIG1 (Q9Y6D6)
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1)
Gene: ARFGEF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 404 Hs			1 1849
+	Hs
		1031127 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		BIG1_HUMAN (1-1849): 0: 2070: 100.00
+	Hs
		599036 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		BIG1_HUMAN (1-1849): 0: 2070: 100.00
+	Hs
		172309 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		BIG2_HUMAN (6-1841): 0: 1847: 74.23
+	Hs
		1031126 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		BIG2_HUMAN (6-1841): 0: 1847: 74.23
+	Hs
		599035 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		BIG2_HUMAN (6-1841): 0: 1847: 74.23
+	Hs
		172151 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		GBF1_HUMAN (1333-1598): 2.53e-45: 183: 14.48
+	Hs
		172085 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		MON2_HUMAN (31-245): 2.86e-35: 150: 17.12
+	Hs
		1031033 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		GBF1_HUMAN (1333-1598): 2.53e-45: 183: 14.48
+	Hs
		723063 OPRM_HUMAN (2-382): 6.04e-76: 242: 20.31		MON2_HUMAN (31-245): 2.86e-35: 150: 17.12
+	Hs
		172032 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		BIG3_HUMAN (37-237): 6.92e-11: 70: 20.29
+	Hs
		1136952 LPAR4_HUMAN (38-331): 1.5e-83: 261: 22.33		BIG3_HUMAN (37-237): 6.92e-11: 70: 20.29
+	Hs
		1030949 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		BIG3_HUMAN (37-237): 6.92e-11: 70: 20.29
+	Hs
		598989 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		GBF1_HUMAN (1333-1598): 2.53e-45: 183: 14.48
+	Hs
		1067528 P2RY6_HUMAN (49-330): 3.68e-23: 100: 26.87		MON2_HUMAN (31-245): 2.86e-35: 150: 17.12
+	Hs
		81923 P2RY6_HUMAN (49-330): 3.68e-23: 100: 26.87		B7ZM73_HUMAN (31-245): 2.69e-35: 150: 17.12
+	Hs
		598957 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		BIG3_HUMAN (37-237): 6.92e-11: 70: 20.29