HitPredict

Interactor 1: CASC3 (O15234)
Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz)
Gene: CASC3

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 703 Hs			1 523
+	Hs
		172817 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		172895 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		613456 MDC1_HUMAN (26-703): 5.64e-39: 157: 9.51		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		172855 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		1262685 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		516595 KMT2C_HUMAN (265-696): 9.73e-14: 77.5: 13.27		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		516606 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		1069753 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		1031402 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83