HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: AP4B1 (Q9Y6B7)
AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin)
Gene: AP4B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 739
+	Hs
		172677 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP2B1_HUMAN (3-611): 0: 562: 28.53
+	Hs
		172746 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1B1_HUMAN (3-617): 0: 552: 28.57
+	Xl
		1237746 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q7ZYG7_XENLA (3-611): 0: 560: 28.69
+	Xl
		50981 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		A1L2H5_XENLA (3-624): 0: 544: 27.78
+	Hs
		172297 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1G1_HUMAN (6-601): 9.59e-154: 469: 14.02
+	Xl
		1232891 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6GPE1_XENLA (6-631): 1.63e-152: 465: 13.80
+	Hs
		126024 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP3B1_HUMAN (3-612): 8.96e-143: 447: 21.09
+	Hs
		172378 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP2A1_HUMAN (5-698): 2.14e-143: 446: 14.27
+	Hs
		172338 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1G2_HUMAN (5-598): 1.92e-142: 438: 14.89
+	Xl
		1197981 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q52KY5_XENLA (3-620): 3.56e-141: 444: 21.47
+	Sc
		691598 XPO1_YEAST (14-1067): 0: 848: 46.08		AP2B_YEAST (20-630): 7.78e-149: 452: 21.96
+	Hs
		173495 XPO1_HUMAN (1-1071): 0: 1022: 100.00		COPG2_HUMAN (28-523): 1.56e-76: 266: 18.80
+	Hs
		173621 XPO1_HUMAN (1-1071): 0: 1022: 100.00		COPG1_HUMAN (31-522): 2.42e-75: 262: 17.00
+	Sc
		721835 XPO1_YEAST (14-1067): 0: 848: 46.08		AP1B1_YEAST (2-579): 3.65e-141: 433: 26.09
+	Xl
		1237641 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6P7I2_XENLA (31-554): 1.43e-74: 260: 16.94
+	Xl
		1231616 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		COPG2_XENLA (28-522): 6.56e-74: 258: 18.25
+	Sc
		722047 XPO1_YEAST (14-1067): 0: 848: 46.08		AP3B_YEAST (11-538): 6.6e-107: 346: 20.20
+	Hs
		1083333 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		AP1B1_HUMAN (3-617): 0: 552: 28.57
+	Mm
		1423790 XPOT_MOUSE (29-1023): 6.35e-125: 407: 14.83		AP3B1_MOUSE (3-602): 5.81e-141: 443: 21.69
+	Hs
		323800 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		AP2A2_HUMAN (5-599): 1.68e-139: 435: 14.84