Protein: COPG2
Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP)

Gene: COPG2
Organism: Homo sapiens
Interactions: 225
UniProt ID: Q9UBF2

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005198 - structural molecule activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1458365

COPG1
Coatomer subunit gamma-1

5

15

Small-scale

0.921

High

921820

COPB
Coatomer subunit beta

4

17

Small-scale

0.887

High

964078

COPZ1
Coatomer subunit zeta-1

2

20

High-throughput

0.811

High

773675

COPB2
Coatomer subunit beta'

2

7

Small-scale

0.789

High

873344

COPD
Coatomer subunit delta

2

2

Small-scale

0.789

High

922069

COPA
Coatomer subunit alpha

2

7

Small-scale

0.789

High

1015147

ARF5
ADP-ribosylation factor 5

2

19

High-throughput

0.737

High

407136

HG2A
HLA class II histocompatibility antigen gamma chain

4

1

High-throughput

0.699

High

1447903

SAR1A
Small COPII coat GTPase SAR1A

1

20

High-throughput

0.691

High

158343

COPE
Coatomer subunit epsilon

3

3

High-throughput

0.667

High

1401898

NUDC1
NudC domain-containing protein 1

3

2

High-throughput

0.662

High

699217

CALX
Calnexin

3

3

High-throughput

0.657

High

1316314

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

2

10

High-throughput

0.628

High

397127

ESR1
Estrogen receptor

3

15

High-throughput

0.624

High

612325

ARF4
ADP-ribosylation factor 4

1

19

High-throughput

0.618

High

958827

ARF3
ADP-ribosylation factor 3

1

19

High-throughput

0.618

High

975290

ARF6
ADP-ribosylation factor 6

1

19

High-throughput

0.618

High

1458349

COPG2
Coatomer subunit gamma-2

1

15

Small-scale

0.618

High

951492

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.611

High

218903

TGON2
Trans-Golgi network integral membrane protein 2

2

12

High-throughput

0.588

High

889030

TMEDA
Transmembrane emp24 domain-containing protein 10

2

7

Small-scale

0.585

High

1352392

RHBL4
Rhomboid-related protein 4

2

2

Small-scale

0.584

High

1364645

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

6

Small-scale

0.584

High

1436526

ECT2
Protein ECT2

2

13

High-throughput

0.584

High

535624

BIP
Endoplasmic reticulum chaperone BiP

2

6

High-throughput

0.571

High

1367484

ESR2
Estrogen receptor beta

3

15

High-throughput

0.569

High

640362

DRD1
D(1A) dopamine receptor

1

4

Small-scale

0.561

High

1209755

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

8

High-throughput

0.552

High

50722

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.536

High

329026

RTN3
Reticulon-3

1

5

High-throughput

0.536

High

564492

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.536

High

904178

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.536

High

1145707

RCN1
Reticulocalbin-1

1

1

High-throughput

0.536

High

1203819

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1258827

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.536

High

1329740

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

12

High-throughput

0.536

High

1340118

ATLA2
Atlastin-2

1

7

High-throughput

0.536

High

1340974

MCFD2
Multiple coagulation factor deficiency protein 2

1

1

High-throughput

0.536

High

1404258

SEC62
Translocation protein SEC62

1

1

High-throughput

0.536

High

1430994

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.536

High

831577

CCNF
Cyclin-F

1

3

High-throughput

0.515

High

1458363

MAGD1
Melanoma-associated antigen D1

1

4

High-throughput

0.515

High

184934

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.513

High

297285

PRAF3
PRA1 family protein 3

1

0

High-throughput

0.513

High

460285

CD3E
T-cell surface glycoprotein CD3 epsilon chain

1

0

High-throughput

0.513

High

1258846

CYS1
Cystin-1

1

0

High-throughput

0.513

High

1349383

RDH11
Retinol dehydrogenase 11

1

0

High-throughput

0.513

High

1420171

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

1434660

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

187203

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.489

High

261669

CATL2
Cathepsin L2

1

1

High-throughput

0.489

High

373386

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.489

High

1008058

KCJ10
ATP-sensitive inward rectifier potassium channel 10

1

1

High-throughput

0.489

High

1111331

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.489

High

1134559

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

8

High-throughput

0.489

High

1142202

P2RY6
P2Y purinoceptor 6

1

3

High-throughput

0.489

High

1401005

PSKH2
Serine/threonine-protein kinase H2

1

3

High-throughput

0.489

High

1404471

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.489

High

1439745

APMAP
Adipocyte plasma membrane-associated protein

1

1

High-throughput

0.489

High

1458361

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.489

High

140017

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

5

High-throughput

0.479

High

173495

XPO1
Exportin-1

1

14

High-throughput

0.479

High

247455

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

7

High-throughput

0.479

High

343092

HERC2
E3 ubiquitin-protein ligase HERC2

1

6

High-throughput

0.479

High

346440

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

353603

AGR2
Anterior gradient protein 2 homolog

1

7

High-throughput

0.479

High

604255

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

630072

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

731667

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

888367

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.479

High

895130

EMD
Emerin

1

1

High-throughput

0.479

High

928720

PMS2
Mismatch repair endonuclease PMS2

1

3

High-throughput

0.479

High

1035965

KIF23
Kinesin-like protein KIF23

1

10

High-throughput

0.479

High

1110144

HDAC1
Histone deacetylase 1

1

6

High-throughput

0.479

High

1114532

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1203096

TM41B
Transmembrane protein 41B

1

1

High-throughput

0.479

High

1231482

ATLA3
Atlastin-3

1

7

High-throughput

0.479

High

1235261

ANO7
Anoctamin-7

1

2

Small-scale

0.479

High

1245145

RHDF2
Inactive rhomboid protein 2

1

2

High-throughput

0.479

High

1249290

LMBRL
Protein LMBR1L

1

4

High-throughput

0.479

High

1288598

ZN598
E3 ubiquitin-protein ligase ZNF598

1

11

High-throughput

0.479

High

1289682

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1335028

SERB1
SERPINE1 mRNA-binding protein 1

1

6

High-throughput

0.479

High

1363879

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

6

High-throughput

0.479

High

1370429

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.479

High

1380678

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1393788

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.479

High

1401724

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

5

High-throughput

0.479

High

1405695

NECD
Necdin

1

4

High-throughput

0.479

High

1433100

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

1433348

GLP3L
Golgi phosphoprotein 3-like

1

5

Small-scale

0.479

High

1433365

GOLP3
Golgi phosphoprotein 3

1

5

Small-scale

0.479

High

1438791

NEK6
Serine/threonine-protein kinase Nek6

1

4

High-throughput

0.479

High

1452718

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1453012

TLS1
Splicing factor C9orf78

1

6

High-throughput

0.479

High

1458351

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1458352

TES
Testin

1

4

High-throughput

0.479

High

1458353

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

1458356

FZR1
Fizzy-related protein homolog

1

8

High-throughput

0.479

High

347385

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.458

High

350164

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

847734

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

982569

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

1233854

GRAM4
GRAM domain-containing protein 4

1

0

Small-scale

0.458

High

1448295

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1458360

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

48835

ESYT2
Extended synaptotagmin-2

1

7

High-throughput

0.445

High

60437

NBAS
NBAS subunit of NRZ tethering complex

1

1

High-throughput

0.445

High

104379

F5H6I7
Atlastin GTPase 3

1

7

High-throughput

0.445

High

211874

ZW10
Centromere/kinetochore protein zw10 homolog

1

1

High-throughput

0.445

High

213663

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

1

High-throughput

0.445

High

215677

EMC8
ER membrane protein complex subunit 8

1

1

High-throughput

0.445

High

275573

RTN2
Reticulon-2

1

5

High-throughput

0.445

High

283382

ERLN1
Erlin-1

1

1

High-throughput

0.445

High

296587

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.445

High

333246

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

4

High-throughput

0.445

High

360143

NB5R3
NADH-cytochrome b5 reductase 3

1

2

High-throughput

0.445

High

462689

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.445

High

530502

TAU
Microtubule-associated protein tau

1

18

High-throughput

0.445

High

567106

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

1

High-throughput

0.445

High

698057

CALR
Calreticulin

1

3

High-throughput

0.445

High

877031

KC1A
Casein kinase I isoform alpha

1

3

High-throughput

0.445

High

883164

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

1

High-throughput

0.445

High

903819

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.445

High

987254

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

13

High-throughput

0.445

High

1009905

NUCB2
Nucleobindin-2

1

1

High-throughput

0.445

High

1027228

REEP5
Receptor expression-enhancing protein 5

1

2

High-throughput

0.445

High

1097072

PRDX4
Peroxiredoxin-4

1

1

High-throughput

0.445

High

1131420

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.445

High

1136401

EMC2
ER membrane protein complex subunit 2

1

2

High-throughput

0.445

High

1139295

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

1

High-throughput

0.445

High

1139410

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

2

High-throughput

0.445

High

1146653

TMED2
Transmembrane emp24 domain-containing protein 2

1

7

High-throughput

0.445

High

1147871

DHC24
Delta(24)-sterol reductase

1

2

High-throughput

0.445

High

1152889

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

3

High-throughput

0.445

High

1199290

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

5

High-throughput

0.445

High

1248686

LCLT1
Lysocardiolipin acyltransferase 1

1

1

High-throughput

0.445

High

1327995

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

1

High-throughput

0.445

High

1330426

EMC1
ER membrane protein complex subunit 1

1

2

High-throughput

0.445

High

1334049

DHB11
Estradiol 17-beta-dehydrogenase 11

1

6

High-throughput

0.445

High

1335759

MOT11
Monocarboxylate transporter 11

1

4

High-throughput

0.445

High

1337709

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.445

High

1337993

ZNT7
Zinc transporter 7

1

6

High-throughput

0.445

High

1338235

VP37A
Vacuolar protein sorting-associated protein 37A

1

1

High-throughput

0.445

High

1346816

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

6

High-throughput

0.445

High

1358391

SCFD1
Sec1 family domain-containing protein 1

1

3

High-throughput

0.445

High

1360586

ATLA1
Atlastin-1

1

7

High-throughput

0.445

High

1363475

S39A7
Zinc transporter SLC39A7

1

1

High-throughput

0.445

High

1381544

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

5

High-throughput

0.445

High

1386227

ASTRA
Protein Aster-A

1

3

High-throughput

0.445

High

1396061

SCYL1
N-terminal kinase-like protein

1

6

High-throughput

0.445

High

1412162

ERP44
Endoplasmic reticulum resident protein 44

1

1

High-throughput

0.445

High

1412711

ESYT1
Extended synaptotagmin-1

1

6

High-throughput

0.445

High

1419929

WDR11
WD repeat-containing protein 11

1

1

High-throughput

0.445

High

1421173

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.445

High

1430088

RGAP1
Rac GTPase-activating protein 1

1

8

High-throughput

0.445

High

1432074

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

1

High-throughput

0.445

High

1432772

TMX1
Thioredoxin-related transmembrane protein 1

1

4

High-throughput

0.445

High

1446935

RTN4
Reticulon-4

1

5

High-throughput

0.445

High

1449579

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

6

High-throughput

0.445

High

1450855

TM38B
Trimeric intracellular cation channel type B

1

1

High-throughput

0.445

High

1452912

TECR
Very-long-chain enoyl-CoA reductase

1

1

High-throughput

0.445

High

1453821

VAPA
Vesicle-associated membrane protein-associated protein A

1

4

High-throughput

0.445

High

1458358

DHRS7
Dehydrogenase/reductase SDR family member 7

1

4

High-throughput

0.445

High

1458359

TMED5
Transmembrane emp24 domain-containing protein 5

1

7

High-throughput

0.445

High

1458364

SERC
Phosphoserine aminotransferase

1

1

High-throughput

0.445

High

247005

KDM1A
Lysine-specific histone demethylase 1A

1

2

High-throughput

0.437

High

325147

HEXI1
Protein HEXIM1

1

8

High-throughput

0.437

High

327486

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

412744

NTRK1
High affinity nerve growth factor receptor

1

16

High-throughput

0.437

High

572405

AT1B2
Sodium/potassium-transporting ATPase subunit beta-2

1

1

High-throughput

0.437

High

576691

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

1

High-throughput

0.437

High

589932

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

696751

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

710771

EPHA8
Ephrin type-A receptor 8

1

6

High-throughput

0.437

High

720349

UFO
Tyrosine-protein kinase receptor UFO

1

13

Small-scale

0.437

High

769408

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

777783

VGFR3
Vascular endothelial growth factor receptor 3

1

5

High-throughput

0.437

High

879571

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.437

High

895222

5HT6R
5-hydroxytryptamine receptor 6

1

5

Small-scale

0.437

High

1100485

TIF1B
Transcription intermediary factor 1-beta

1

4

High-throughput

0.437

High

1148882

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

2

High-throughput

0.437

High

1155859

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.437

High

1255922

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1276906

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1313496

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.437

High

1313867

S15A3
Solute carrier family 15 member 3

1

5

High-throughput

0.437

High

1324098

RHG24
Rho GTPase-activating protein 24

1

6

High-throughput

0.437

High

1364288

TOPB1
DNA topoisomerase 2-binding protein 1

1

2

High-throughput

0.437

High

1433795

SENP3
Sentrin-specific protease 3

1

3

Small-scale

0.437

High

1434126

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1448223

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.437

High

1458357

ALK
ALK tyrosine kinase receptor

1

18

High-throughput

0.437

High

104241

F5H1C8
Solute carrier family 15 member 3

1

5

High-throughput

0.407

High

166437

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

6

High-throughput

0.407

High

319036

MICA2
[F-actin]-monooxygenase MICAL2

1

3

High-throughput

0.407

High

754116

CD80
T-lymphocyte activation antigen CD80

1

1

High-throughput

0.407

High

771258

APJ
Apelin receptor

1

2

High-throughput

0.407

High

844888

EAA1
Excitatory amino acid transporter 1

1

2

High-throughput

0.407

High

1211972

S35F1
Solute carrier family 35 member F1

1

2

High-throughput

0.407

High

1273818

NIPA1
Magnesium transporter NIPA1

1

3

High-throughput

0.407

High

1323776

S39AB
Zinc transporter ZIP11

1

1

High-throughput

0.407

High

1412004

PXL2A
Peroxiredoxin-like 2A

1

1

High-throughput

0.407

High

1413793

NDC1
Nucleoporin NDC1

1

1

High-throughput

0.407

High

1451099

GPTC2
G patch domain-containing protein 2

1

1

High-throughput

0.407

High

1452614

PSD3
PH and SEC7 domain-containing protein 3

1

4

High-throughput

0.407

High

1458350

S53A1
Solute carrier family 53 member 1

1

1

High-throughput

0.407

High

1458355

TTC7A
Tetratricopeptide repeat protein 7A

1

1

Small-scale

0.407

High

1438824

HES4
Transcription factor HES-4

1

0

High-throughput

0.292

High

231022

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.279

Low

295001

RPP40
Ribonuclease P protein subunit p40

1

0

High-throughput

0.279

Low

658942

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

0

High-throughput

0.279

Low

784756

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

556394

CADH1
Cadherin-1

1

0

High-throughput

0.249

Low

643117

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low

993912

TYB10
Thymosin beta-10

1

0

High-throughput

0.249

Low

1226549

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1258405

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1411956

PELO
Protein pelota homolog

1

0

High-throughput

0.249

Low

1429382

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1458354

RCOR1
REST corepressor 1

1

0

High-throughput

0.249

Low

1458362

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.249

Low

1149

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

262328

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025