HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: Q3YBA8 (Q3YBA8)
14-3-3 tau splice variant
Gene: Q3YBA8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	16511560, 16511572
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 74
+	Hs
		179702 MDM4_HUMAN (1-490): 0: 692: 100.00		1433E_HUMAN (2-51): 2.35e-22: 87.7: 54.72
+	Hs
		179713 MDM4_HUMAN (1-490): 0: 692: 100.00		1433F_HUMAN (2-51): 1.24e-21: 85.6: 62.26
+	Hs
		179674 MDM4_HUMAN (1-490): 0: 692: 100.00		1433T_HUMAN (1-51): 2.72e-20: 82.3: 87.04
+	Hs
		179706 MDM4_HUMAN (1-490): 0: 692: 100.00		1433Z_HUMAN (1-51): 4.61e-20: 81.5: 79.63
+	Hs
		179677 MDM4_HUMAN (1-490): 0: 692: 100.00		1433B_HUMAN (1-51): 6.85e-20: 81.1: 77.78
+	Hs
		179699 MDM4_HUMAN (1-490): 0: 692: 100.00		1433G_HUMAN (1-51): 1.17e-19: 80.4: 62.96
+	Hs
		179678 MDM4_HUMAN (1-490): 0: 692: 100.00		1433S_HUMAN (1-51): 1.77e-19: 80.2: 68.52
+	Mm
		205235 MDM4_MOUSE (1-490): 0: 678: 83.91		1433G_MOUSE (1-51): 1.17e-19: 80.4: 62.96
+	Hs
		690912 MDM2_HUMAN (2-488): 0: 554: 31.56		1433T_HUMAN (1-51): 2.72e-20: 82.3: 87.04
+	Hs
		990103 MDM2_HUMAN (2-488): 0: 554: 31.56		1433Z_HUMAN (1-51): 4.61e-20: 81.5: 79.63
+	Hs
		730517 MDM2_HUMAN (2-488): 0: 554: 31.56		1433S_HUMAN (1-51): 1.77e-19: 80.2: 68.52
+	Mm
		662962 MDM2_MOUSE (2-488): 0: 532: 29.78		1433T_MOUSE (1-51): 3.81e-20: 81.9: 87.04