HitPredict

Interactor 1: YKT6 (O15498)
Synaptobrevin homolog YKT6 (EC 2.3.1.-)
Gene: YKT6

Interactor 2: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005768 - endosome GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0043025 - neuronal cell body
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 215
+	Hs
		180835 YKT6_HUMAN (1-198): 2.95e-72: 218: 100.00		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Sc
		350867 YKT6_YEAST (1-198): 9.98e-69: 209: 47.00		YPT1_YEAST (14-213): 5.55e-88: 259: 39.02
+	Hs
		180855 YKT6_HUMAN (1-198): 2.95e-72: 218: 100.00		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		263168 SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60		RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00
+	Hs
		263198 SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Hs
		263215 SC22B_HUMAN (1-196): 2.72e-63: 196: 19.60		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		592170 VAMP7_HUMAN (28-193): 7.9e-57: 180: 22.03		RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00
+	Hs
		844447 VAMP7_HUMAN (28-193): 7.9e-57: 180: 22.03		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Hs
		850554 VAMP7_HUMAN (28-193): 7.9e-57: 180: 22.03		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Sc
		350845 SEC22_YEAST (1-192): 2.06e-45: 151: 21.32		YPT1_YEAST (14-213): 5.55e-88: 259: 39.02