HitPredict

Interactor 1: DDX3Y (O15523)
ATP-dependent RNA helicase DDX3Y (EC 3.6.4.13) (DEAD box protein 3, Y-chromosomal)
Gene: DDX3Y

Interactor 2: ERR3 (P62508)
Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)
Gene: ESRRG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 660 Hs			1 458
+	Hs
		181675 DDX3Y_HUMAN (1-660): 0: 614: 100.00		ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61
+	Hs
		133828 DDX3X_HUMAN (1-660): 0: 602: 91.84		ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61
+	Hs
		133914 DDX3X_HUMAN (1-660): 0: 602: 91.84		HNF4A_HUMAN (82-454): 3.83e-112: 340: 26.47
+	Mm
		509320 DDX3X_MOUSE (1-660): 0: 600: 91.24		RARA_MOUSE (62-455): 8.16e-112: 339: 28.92
+	Hs
		133881 DDX3X_HUMAN (1-660): 0: 602: 91.84		NR4A1_HUMAN (42-454): 8.47e-108: 333: 29.16
+	Hs
		134142 DDX3X_HUMAN (1-660): 0: 602: 91.84		ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50
+	Hs
		368944 DDX5_HUMAN (89-655): 1.67e-158: 471: 34.96		ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61
+	Hs
		370142 DDX17_HUMAN (123-652): 1.07e-152: 460: 36.48		ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61
+	Mm
		509328 Q8BTS0_MOUSE (86-655): 1.84e-158: 471: 34.78		RARA_MOUSE (62-455): 8.16e-112: 339: 28.92
+	Hs
		571310 DDX5_HUMAN (89-655): 1.67e-158: 471: 34.96		NR4A1_HUMAN (42-454): 8.47e-108: 333: 29.16