HitPredict

Interactor 1: TPSN (O15533)
Tapasin (TPN) (TPSN) (NGS-17) (TAP-associated protein) (TAP-binding protein)
Gene: TAPBP

Interactor 2: TAP1 (Q03518)
Antigen peptide transporter 1 (APT1) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein) (RING4)
Gene: TAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.732

The method score is based on:

Property Details
Experiments 12213826, 11884415, 11823531, 17055437, 18802093, 19201886
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0019885 - antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0030670 - phagocytic vesicle membrane
GO:0033116 - endoplasmic reticulum-Golgi intermediate compartment membrane
and 5 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 448
Hs

1 748
+ Rn
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024