HitPredict

Interactor 1: P4HA2 (O15460)
Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)
Gene: P4HA2

Interactor 2: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	28514442, 33961781, 26848503, unassigned3799
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 1464
+	Hs
		191279 P4HA2_HUMAN (1-535): 0: 725: 100.00		CO5A2_HUMAN (1-1464): 0: 691: 58.00
+	Hs
		384099 P4HA1_HUMAN (6-535): 0: 649: 62.03		CO1A1_HUMAN (1-1464): 0: 674: 100.00
+	Hs
		191284 P4HA2_HUMAN (1-535): 0: 725: 100.00		COBA1_HUMAN (3-686): 5.48e-46: 184: 36.59
+	Hs
		191292 P4HA2_HUMAN (1-535): 0: 725: 100.00		CO5A1_HUMAN (3-654): 7.02e-36: 151: 36.76
+	Hs
		191319 P4HA2_HUMAN (1-535): 0: 725: 100.00		COGA1_HUMAN (988-1266): 1.3e-11: 71.8: 23.34
+	Hs
		191281 P4HA2_HUMAN (1-535): 0: 725: 100.00		CO4A2_HUMAN (3-160): 2.01e-11: 71.4: 21.95
+	Hs
		191371 P4HA2_HUMAN (1-535): 0: 725: 100.00		COMA1_HUMAN (14-340): 2.15e-10: 67.9: 26.90
+	Hs
		566977 P4HA1_HUMAN (6-535): 0: 649: 62.03		CO4A6_HUMAN (8-289): 5.09e-23: 109: 25.25
+	Hs
		384238 P4HA1_HUMAN (6-535): 0: 649: 62.03		CO2A1_HUMAN (3-246): 5.62e-17: 89.5: 27.24
+	Hs
		566969 P4HA1_HUMAN (6-535): 0: 649: 62.03		COGA1_HUMAN (988-1266): 1.3e-11: 71.8: 23.34
+	Hs
		471578 P4HA1_HUMAN (6-535): 0: 649: 62.03		CO4A2_HUMAN (3-160): 2.01e-11: 71.4: 21.95