HitPredict

Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1

Interactor 2: P4HA1 (P13674)
Prolyl 4-hydroxylase subunit alpha-1 (4-PH alpha-1) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1)
Gene: P4HA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26848503
Identification Methods	cross-linking study, anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0030199 - collagen fibril organization
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1464 Hs			1 534
+	Hs
		191279 CO5A2_HUMAN (1-1464): 0: 691: 58.00		P4HA2_HUMAN (1-534): 0: 695: 61.61
+	Hs
		191277 CO1A1_HUMAN (1-1464): 0: 674: 100.00		P4HA2_HUMAN (1-534): 0: 695: 61.61
+	Hs
		191284 COBA1_HUMAN (3-686): 5.48e-46: 184: 36.59		P4HA2_HUMAN (1-534): 0: 695: 61.61
+	Hs
		191292 CO5A1_HUMAN (3-654): 7.02e-36: 151: 36.76		P4HA2_HUMAN (1-534): 0: 695: 61.61
+	Hs
		566977 CO4A6_HUMAN (8-289): 5.09e-23: 109: 25.25		P4HA1_HUMAN (1-534): 0: 716: 100.00
+	Hs
		384238 CO2A1_HUMAN (3-246): 5.62e-17: 89.5: 27.24		P4HA1_HUMAN (1-534): 0: 716: 100.00
+	Hs
		566969 COGA1_HUMAN (988-1266): 1.3e-11: 71.8: 23.34		P4HA1_HUMAN (1-534): 0: 716: 100.00
+	Hs
		471578 CO4A2_HUMAN (3-160): 2.01e-11: 71.4: 21.95		P4HA1_HUMAN (1-534): 0: 716: 100.00
+	Hs
		191319 COGA1_HUMAN (988-1266): 1.3e-11: 71.8: 23.34		P4HA2_HUMAN (1-534): 0: 695: 61.61
+	Hs
		191281 CO4A2_HUMAN (3-160): 2.01e-11: 71.4: 21.95		P4HA2_HUMAN (1-534): 0: 695: 61.61
+	Hs
		191371 COMA1_HUMAN (14-340): 2.15e-10: 67.9: 26.90		P4HA2_HUMAN (1-534): 0: 695: 61.61