HitPredict

Interactor 1: TTI1 (O43156)
TELO2-interacting protein 1 homolog (Protein SMG10)
Gene: TTI1

Interactor 2: RUVB2 (Q9Y230)
RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta)
Gene: RUVBL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	28561026, 35271311, 17643375, 20801936, 20371770
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006338 - chromatin remodeling GO:0050821 - protein stabilization
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 463
+	Hs
		195952 TTI1_HUMAN (1-1089): 0: 1217: 100.00		RUVB1_HUMAN (8-451): 0: 655: 42.67
+	Dm
		1358866 Q9VH80_DROME (14-1046): 0: 920: 20.66		RUVB2_DROME (6-458): 0: 681: 78.15
+	Dm
		1366581 Q9VH80_DROME (14-1046): 0: 920: 20.66		RUVB1_DROME (8-452): 0: 619: 44.32
+	Sp
		293725 TTI1_SCHPO (22-1082): 0: 788: 18.28		RUVB2_SCHPO (7-451): 0: 660: 70.79
+	Sp
		293729 TTI1_SCHPO (22-1082): 0: 788: 18.28		RUVB1_SCHPO (9-447): 0: 625: 44.03
+	Sc
		732574 TTI1_YEAST (30-1043): 0: 762: 17.34		RUVB2_YEAST (7-451): 0: 650: 68.76