HitPredict

Interactor 1: SRGP3 (O43295)
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)
Gene: SRGAP3

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1099 Hs			1 1193
+	Hs
		1133693 RHG21_HUMAN (293-1092): 4.39e-86: 308: 17.64		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		63075 RHG42_HUMAN (148-969): 1.9e-92: 317: 13.35		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		724864 RHG21_HUMAN (293-1092): 4.39e-86: 308: 17.64		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		70674 MYO9A_HUMAN (130-972): 6.47e-85: 305: 12.51		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		1068686 RHG23_HUMAN (405-1090): 2.14e-84: 302: 15.65		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		64621 RHG32_HUMAN (311-1098): 9.49e-85: 304: 14.43		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		1068712 3BP1_HUMAN (272-901): 4.24e-76: 267: 17.75		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		725200 RHG24_HUMAN (520-701): 3.97e-23: 108: 32.09		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		724914 RHG24_HUMAN (520-701): 3.97e-23: 108: 32.09		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04