HitPredict

Interactor 1: SRGP3 (O43295)
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)
Gene: SRGAP3

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25819436
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1099 Hs			1 368
+	Hs
		200232 SRGP3_HUMAN (1-1099): 0: 799: 100.00		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		200212 SRGP3_HUMAN (1-1099): 0: 799: 100.00		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		253384 SRGP2_HUMAN (1-1087): 0: 675: 57.36		SH3R3_HUMAN (305-362): 1.03e-11: 68.3: 43.55
+	Hs
		1148391 RHG17_HUMAN (224-1051): 4.25e-86: 299: 15.45		SHLB1_HUMAN (10-363): 3.1e-69: 223: 25.28
+	Hs
		1089302 RHG17_HUMAN (224-1051): 4.25e-86: 299: 15.45		RHG44_HUMAN (6-251): 8.5e-47: 172: 22.22
+	Hs
		1052226 RHG17_HUMAN (224-1051): 4.25e-86: 299: 15.45		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		1148385 RHG17_HUMAN (224-1051): 4.25e-86: 299: 15.45		PACN1_HUMAN (16-363): 9.35e-37: 139: 14.89
+	Hs
		1148392 RHG17_HUMAN (224-1051): 4.25e-86: 299: 15.45		3BP1_HUMAN (6-260): 2.89e-33: 132: 18.62
+	Hs
		1089311 RHG44_HUMAN (267-1078): 5.9e-82: 287: 14.95		3BP1_HUMAN (6-260): 2.89e-33: 132: 18.62
+	Hs
		1357492 3BP1_HUMAN (272-901): 4.24e-76: 267: 17.75		PACN2_HUMAN (16-364): 1.92e-34: 134: 14.97
+	Hs
		64687 RHG32_HUMAN (311-1098): 9.49e-85: 304: 14.43		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924636 RHG17_HUMAN (224-1051): 4.25e-86: 299: 15.45		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924608 Q1RLN5_HUMAN (486-694): 7.15e-69: 249: 24.76		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924686 RHG12_HUMAN (486-694): 3e-68: 248: 24.76		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		1052250 RHG24_HUMAN (520-701): 3.97e-23: 108: 32.09		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		1052327 RHG35_HUMAN (517-668): 1.93e-19: 97.1: 34.42		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		924893 RHG35_HUMAN (517-668): 1.93e-19: 97.1: 34.42		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38