HitPredict

Interactor 1: CLD4 (O35054)
Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor)
Gene: Cldn4

Interactor 2: ZO1 (P39447)
Tight junction protein 1 (Tight junction protein ZO-1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: Tjp1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10601346
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0016020 - membrane GO:0016324 - apical plasma membrane GO:0016327 - apicolateral plasma membrane and 1 others more... GO:0070160 - tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 210 Mm			1 1745
+	Hs
		337870 CLD7_HUMAN (1-210): 1.38e-88: 261: 47.39		ZO1_HUMAN (1-1745): 0: 1015: 90.79
+	Mm
		312569 CLD1_MOUSE (1-210): 3.45e-87: 257: 44.55		ZO1_MOUSE (1-1745): 0: 1017: 100.00
+	Mm
		811962 CLD7_MOUSE (1-210): 2.17e-84: 250: 50.24		ZO1_MOUSE (1-1745): 0: 1017: 100.00
+	Mm
		811961 CLD8_MOUSE (1-199): 3.37e-81: 242: 45.05		ZO1_MOUSE (1-1745): 0: 1017: 100.00
+	Hs
		942277 CLD8_HUMAN (1-199): 6.27e-82: 244: 46.54		ZO1_HUMAN (1-1745): 0: 1015: 90.79
+	Hs
		348832 CLD1_HUMAN (1-210): 9.46e-82: 243: 46.92		ZO1_HUMAN (1-1745): 0: 1015: 90.79
+	Hs
		942273 CLD6_HUMAN (1-206): 8.65e-80: 239: 61.65		ZO1_HUMAN (1-1745): 0: 1015: 90.79
+	Hs
		138560 CLD5_HUMAN (1-207): 3.18e-78: 235: 49.05		ZO1_HUMAN (1-1745): 0: 1015: 90.79
+	Mm
		236741 CLD5_MOUSE (1-206): 1.93e-77: 233: 50.24		ZO1_MOUSE (1-1745): 0: 1017: 100.00
+	Hs
		154478 CLD4_HUMAN (1-210): 1.55e-77: 232: 83.33		ZO1_HUMAN (1-1745): 0: 1015: 90.79
+	Mm
		811960 CLD3_MOUSE (3-203): 2.02e-76: 230: 69.65		ZO1_MOUSE (1-1745): 0: 1017: 100.00
+	Hs
		194648 CLD3_HUMAN (3-204): 9.51e-77: 231: 67.00		ZO1_HUMAN (1-1745): 0: 1015: 90.79
+	Hs
		325373 CLD1_HUMAN (1-210): 9.46e-82: 243: 46.92		ZO3_HUMAN (13-927): 8.04e-141: 462: 38.97
+	Mm
		312571 CLD1_MOUSE (1-210): 3.45e-87: 257: 44.55		ZO3_MOUSE (13-925): 3.75e-135: 446: 38.53
+	Mm
		204069 CLD4_MOUSE (1-210): 6.33e-88: 259: 100.00		MPDZ_MOUSE (6-329): 4.52e-23: 109: 17.13
+	Mm
		312570 CLD1_MOUSE (1-210): 3.45e-87: 257: 44.55		MPDZ_MOUSE (6-329): 4.52e-23: 109: 17.13
+	Hs
		154482 CLD4_HUMAN (1-210): 1.55e-77: 232: 83.33		DLG1_HUMAN (1-112): 3.28e-25: 116: 31.58
+	Hs
		348836 CLD1_HUMAN (1-210): 9.46e-82: 243: 46.92		INADL_HUMAN (51-506): 3.53e-15: 84.1: 14.56
+	Mm
		312572 CLD1_MOUSE (1-210): 3.45e-87: 257: 44.55		ZO2_MOUSE (422-924): 2.97e-09: 64.2: 14.97
+	Hs
		348841 CLD1_HUMAN (1-210): 9.46e-82: 243: 46.92		ZO2_HUMAN (399-625): 7.16e-10: 66.5: 18.30