HitPredict

Interactor 1: PBX3 (O35317)
Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3)
Gene: PBX3

Interactor 2: HXC6 (P10629)
Homeobox protein Hox-C6 (Homeobox protein Hox-3.3) (Homeobox protein Hox-6.1)
Gene: Hoxc6

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Homeobox_KN~Homeodomain
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 434 Mm			1 235
+	Mm
		204665 PBX3_MOUSE (1-434): 2.52e-155: 448: 100.00		HXA6_MOUSE (1-219): 6.72e-45: 151: 44.83
+	Mm
		204668 PBX3_MOUSE (1-434): 2.52e-155: 448: 100.00		HXD4_MOUSE (1-227): 2.56e-35: 127: 29.24
+	Hs
		604773 PBX3_HUMAN (1-434): 7.6e-156: 449: 99.77		HXB8_HUMAN (1-234): 1.75e-34: 125: 29.68
+	Mm
		204674 PBX3_MOUSE (1-434): 2.52e-155: 448: 100.00		HXC4_MOUSE (1-234): 3.81e-34: 124: 27.89
+	Mm
		204667 PBX3_MOUSE (1-434): 2.52e-155: 448: 100.00		HXB8_MOUSE (1-234): 1.13e-33: 123: 29.27
+	Mm
		204671 PBX3_MOUSE (1-434): 2.52e-155: 448: 100.00		HXD10_MOUSE (1-204): 7.8e-31: 118: 26.51
+	Mm
		204664 PBX3_MOUSE (1-434): 2.52e-155: 448: 100.00		HXB5_MOUSE (23-216): 5.54e-30: 114: 34.54
+	Mm
		204672 PBX3_MOUSE (1-434): 2.52e-155: 448: 100.00		HXC5_MOUSE (1-207): 1.28e-30: 114: 31.67
+	Hs
		484820 PBX1_HUMAN (1-434): 5.72e-136: 398: 82.07		HXB7_HUMAN (1-211): 2.13e-40: 139: 37.21
+	Mm
		478353 PBX1_MOUSE (1-434): 5.72e-136: 398: 82.07		HXB6_MOUSE (1-219): 7.24e-40: 138: 41.52
+	Hs
		478283 PBX1_HUMAN (1-434): 5.72e-136: 398: 82.07		HXD4_HUMAN (1-230): 3.53e-36: 130: 29.46
+	Hs
		478660 PBX1_HUMAN (1-434): 5.72e-136: 398: 82.07		HXB5_HUMAN (23-213): 1.26e-34: 126: 34.56
+	Hs
		604772 PBX1_HUMAN (1-434): 5.72e-136: 398: 82.07		HXB8_HUMAN (1-234): 1.75e-34: 125: 29.68
+	Mm
		478352 PBX1_MOUSE (1-434): 5.72e-136: 398: 82.07		HXA1_MOUSE (10-216): 1.31e-31: 120: 25.58
+	Mm
		86289 PBX1_MOUSE (1-434): 5.72e-136: 398: 82.07		B9EHK7_MOUSE (10-216): 8.07e-32: 120: 25.58
+	Hs
		725025 PBX1_HUMAN (1-434): 5.72e-136: 398: 82.07		HXC8_HUMAN (1-209): 3.23e-32: 119: 31.34
+	Hs
		184763 PBX1_HUMAN (1-434): 5.72e-136: 398: 82.07		SHOX_HUMAN (126-226): 2.46e-31: 118: 24.75
+	Mm
		478347 PBX1_MOUSE (1-434): 5.72e-136: 398: 82.07		HXA5_MOUSE (30-213): 1.15e-30: 116: 37.50
+	Hs
		823830 PBX1_HUMAN (1-434): 5.72e-136: 398: 82.07		HXC5_HUMAN (1-207): 6.79e-30: 112: 32.00
+	Hs
		823827 PBX1_HUMAN (1-434): 5.72e-136: 398: 82.07		PDX1_HUMAN (123-201): 6.88e-22: 92.8: 53.41