HitPredict

Interactor 1: PSDE (O35593)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (MAD1)
Gene: Psmd14

Interactor 2: PSB4 (P99026)
Proteasome subunit beta type-4 (Low molecular mass protein 3) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (Proteasome subunit beta-7) (beta-7)
Gene: Psmb4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	17139257
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Mm			1 264
+	Hs
		137975 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB4_HUMAN (1-264): 5.45e-87: 261: 93.94
+	Dm
		1463629 PSDE_DROME (1-310): 7.18e-114: 333: 88.39		PSB4_DROME (11-263): 4.17e-78: 239: 39.69
+	Dm
		1376917 PSDE_DROME (1-310): 7.18e-114: 333: 88.39		PSA5_DROME (26-255): 2.83e-75: 230: 13.82
+	Hs
		137974 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSA5_HUMAN (26-252): 2.28e-78: 238: 13.28
+	Hs
		137864 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSA7_HUMAN (31-255): 5.85e-77: 235: 14.47
+	Dm
		1264678 PSDE_DROME (1-310): 7.18e-114: 333: 88.39		Q7K148_DROME (24-249): 6.42e-73: 225: 24.34
+	Hs
		137967 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSA2_HUMAN (28-257): 7.75e-75: 229: 14.71
+	Hs
		138044 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSA6_HUMAN (26-261): 1.34e-74: 229: 12.10
+	Dm
		1463631 PSDE_DROME (1-310): 7.18e-114: 333: 88.39		Q9VUJ1_DROME (56-264): 1.61e-70: 219: 16.27
+	Hs
		137977 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB5_HUMAN (16-252): 5.55e-73: 225: 20.68
+	Dm
		821876 PSDE_DROME (1-310): 7.18e-114: 333: 88.39		PSA2_DROME (28-255): 2.02e-69: 215: 14.41
+	Dm
		1463627 PSDE_DROME (1-310): 7.18e-114: 333: 88.39		Q9VJJ0_DROME (55-252): 5.26e-69: 213: 22.11
+	Hs
		138282 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB7_HUMAN (51-253): 3.2e-70: 219: 18.23
+	Hs
		137956 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB1_HUMAN (21-246): 8.72e-67: 209: 22.55
+	Sp
		836445 RPN11_SCHPO (1-309): 7.4e-102: 302: 68.29		PSB2_SCHPO (46-264): 1.95e-72: 224: 18.72
+	Sp
		836455 RPN11_SCHPO (1-309): 7.4e-102: 302: 68.29		PSB7_SCHPO (30-263): 2.39e-72: 224: 40.34
+	Sp
		721229 RPN11_SCHPO (1-309): 7.4e-102: 302: 68.29		PSB5_SCHPO (18-263): 1.13e-69: 217: 21.86
+	Sp
		207224 RPN11_SCHPO (1-309): 7.4e-102: 302: 68.29		PSB1_SCHPO (49-245): 4.86e-63: 198: 18.18
+	Hs
		138018 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		PSB2_HUMAN (56-249): 1.77e-40: 140: 20.51
+	Sp
		836444 RPN11_SCHPO (1-309): 7.4e-102: 302: 68.29		PSB4_SCHPO (55-244): 4.16e-29: 110: 17.71