HitPredict

Interactor 1: NEB1 (O35867)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (PP1bp175) (Protein phosphatase 1 regulatory subunit 9A) (p180)
Gene: Ppp1r9a

Interactor 2: PP1B (P62142)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: Ppp1cb

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	18216290
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Metallophos~PDZ, PDZ~STPPase_N, Metallophos~PDZ_5, PDZ_5~STPPase_N
Common GO terms	GO:0005737 - cytoplasm GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1095 Rn			1 327
+	Hs
		968479 NEB1_HUMAN (1-1094): 1.28e-114: 383: 90.04		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Rn
		205624 NEB1_RAT (1-1095): 1.74e-119: 396: 100.00		PP1G_RAT (1-327): 0: 569: 86.89
+	Hs
		968035 NEB1_HUMAN (1-1094): 1.28e-114: 383: 90.04		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		786928 NEB1_HUMAN (1-1094): 1.28e-114: 383: 90.04		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		967754 DLG2_HUMAN (122-932): 9.35e-58: 217: 12.82		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Rn
		204578 NEB2_RAT (1-827): 6.09e-49: 189: 45.68		PP1B_RAT (1-327): 0: 597: 100.00
+	Hs
		968418 NEB2_HUMAN (1-827): 4.34e-47: 184: 45.38		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Mm
		968505 NEB2_MOUSE (1-827): 2.6e-46: 181: 45.56		PP1B_MOUSE (1-327): 0: 597: 100.00
+	Rn
		204577 NEB2_RAT (1-827): 6.09e-49: 189: 45.68		PP1A_RAT (1-326): 0: 576: 88.79
+	Hs
		967894 DLG3_HUMAN (292-1056): 4.86e-48: 187: 10.28		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		967935 NEB2_HUMAN (1-827): 4.34e-47: 184: 45.38		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Rn
		204579 NEB2_RAT (1-827): 6.09e-49: 189: 45.68		PP1G_RAT (1-327): 0: 569: 86.89
+	Mm
		968127 NEB2_MOUSE (1-827): 2.6e-46: 181: 45.56		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Mm
		968503 DLG4_MOUSE (340-881): 1.09e-38: 157: 12.46		PP1B_MOUSE (1-327): 0: 597: 100.00
+	Hs
		786802 NEB2_HUMAN (1-827): 4.34e-47: 184: 45.38		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Mm
		989679 DLG3_MOUSE (292-1056): 5.25e-46: 181: 10.79		PP1G_MOUSE (1-327): 0: 569: 86.89
+	Mm
		989693 NEB2_MOUSE (1-827): 2.6e-46: 181: 45.56		PP1G_MOUSE (1-327): 0: 569: 86.89
+	Hs
		786575 DLG1_HUMAN (233-1075): 2.33e-43: 173: 10.77		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Mm
		968113 DLG4_MOUSE (340-881): 1.09e-38: 157: 12.46		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Mm
		977638 NEB2_MOUSE (1-827): 2.6e-46: 181: 45.56		PP2AB_MOUSE (8-303): 1.26e-176: 492: 46.13