HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.972

Property	Details
Experiments	15016827, 26186194, 27880917, 28514442, 28330616, 30344098, 33961781, unassigned3799, 24366813
Identification Methods	pull down, far western blotting, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Metallophos~PDZ, Metallophos~PDZ_5, PDZ~STPPase_N, PDZ_5~STPPase_N
Common GO terms	GO:0005737 - cytoplasm GO:0043197 - dendritic spine
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 323 Hs			1 1098
+	Rn
		205624 PP1G_RAT (1-323): 0: 602: 99.69		NEB1_RAT (1-1093): 5.32e-116: 387: 90.04
+	Hs
		968035 PP1A_HUMAN (1-323): 0: 579: 90.66		NEB1_HUMAN (1-1098): 2.87e-121: 401: 100.00
+	Hs
		968479 PP1B_HUMAN (1-322): 0: 560: 86.89		NEB1_HUMAN (1-1098): 2.87e-121: 401: 100.00
+	Rn
		205623 PP1B_RAT (1-322): 0: 560: 86.89		NEB1_RAT (1-1093): 5.32e-116: 387: 90.04
+	Mm
		989679 PP1G_MOUSE (1-323): 0: 602: 99.69		DLG3_MOUSE (311-1098): 1.7e-74: 266: 12.84
+	Hs
		786575 PP1G_HUMAN (1-323): 0: 603: 100.00		DLG1_HUMAN (225-1097): 5.12e-73: 263: 13.80
+	Hs
		967894 PP1A_HUMAN (1-323): 0: 579: 90.66		DLG3_HUMAN (311-1098): 6.1e-72: 258: 12.79
+	Mm
		968113 PP1A_MOUSE (1-323): 0: 579: 90.36		DLG4_MOUSE (376-1098): 2.53e-57: 213: 13.40
+	Hs
		967754 PP1A_HUMAN (1-323): 0: 579: 90.66		DLG2_HUMAN (328-1097): 2.13e-54: 207: 12.44
+	Rn
		204579 PP1G_RAT (1-323): 0: 602: 99.69		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Hs
		786802 PP1G_HUMAN (1-323): 0: 603: 100.00		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39
+	Mm
		989693 PP1G_MOUSE (1-323): 0: 602: 99.69		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Mm
		968503 PP1B_MOUSE (1-322): 0: 560: 86.89		DLG4_MOUSE (376-1098): 2.53e-57: 213: 13.40
+	Rn
		204577 PP1A_RAT (1-323): 0: 579: 90.66		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Mm
		968127 PP1A_MOUSE (1-323): 0: 579: 90.36		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Hs
		967935 PP1A_HUMAN (1-323): 0: 579: 90.66		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39
+	Hs
		967924 PP1A_HUMAN (1-323): 0: 579: 90.66		LRRC7_HUMAN (2-590): 1.25e-41: 169: 13.91
+	Rn
		204578 PP1B_RAT (1-322): 0: 560: 86.89		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Mm
		968505 PP1B_MOUSE (1-322): 0: 560: 86.89		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Hs
		968418 PP1B_HUMAN (1-322): 0: 560: 86.89		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39