HitPredict

Interactor 1: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15016827
Identification Methods	far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Metallophos~PDZ, Metallophos~PDZ_5, PDZ~STPPase_N, PDZ_5~STPPase_N
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Hs			1 1098
+	Rn
		205623 PP1B_RAT (1-327): 0: 597: 100.00		NEB1_RAT (1-1093): 5.32e-116: 387: 90.04
+	Hs
		968035 PP1A_HUMAN (1-326): 0: 576: 88.79		NEB1_HUMAN (1-1098): 2.87e-121: 401: 100.00
+	Hs
		786928 PP1G_HUMAN (1-327): 0: 569: 86.89		NEB1_HUMAN (1-1098): 2.87e-121: 401: 100.00
+	Rn
		205624 PP1G_RAT (1-327): 0: 569: 86.89		NEB1_RAT (1-1093): 5.32e-116: 387: 90.04
+	Mm
		989679 PP1G_MOUSE (1-327): 0: 569: 86.89		DLG3_MOUSE (311-1098): 1.7e-74: 266: 12.84
+	Hs
		967894 PP1A_HUMAN (1-326): 0: 576: 88.79		DLG3_HUMAN (311-1098): 6.1e-72: 258: 12.79
+	Hs
		786575 PP1G_HUMAN (1-327): 0: 569: 86.89		DLG1_HUMAN (225-1097): 5.12e-73: 263: 13.80
+	Mm
		968503 PP1B_MOUSE (1-327): 0: 597: 100.00		DLG4_MOUSE (376-1098): 2.53e-57: 213: 13.40
+	Mm
		968113 PP1A_MOUSE (1-326): 0: 576: 88.49		DLG4_MOUSE (376-1098): 2.53e-57: 213: 13.40
+	Hs
		967754 PP1A_HUMAN (1-326): 0: 576: 88.79		DLG2_HUMAN (328-1097): 2.13e-54: 207: 12.44
+	Rn
		204578 PP1B_RAT (1-327): 0: 597: 100.00		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Mm
		968505 PP1B_MOUSE (1-327): 0: 597: 100.00		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Hs
		968418 PP1B_HUMAN (1-327): 0: 597: 100.00		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39
+	Rn
		204577 PP1A_RAT (1-326): 0: 576: 88.79		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Rn
		204579 PP1G_RAT (1-327): 0: 569: 86.89		NEB2_RAT (1-824): 9.95e-47: 183: 43.40
+	Mm
		968127 PP1A_MOUSE (1-326): 0: 576: 88.49		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Hs
		967935 PP1A_HUMAN (1-326): 0: 576: 88.79		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39
+	Hs
		967924 PP1A_HUMAN (1-326): 0: 576: 88.79		LRRC7_HUMAN (2-590): 1.25e-41: 169: 13.91
+	Mm
		989693 PP1G_MOUSE (1-327): 0: 569: 86.89		NEB2_MOUSE (1-824): 1.22e-44: 176: 43.40
+	Hs
		786802 PP1G_HUMAN (1-327): 0: 569: 86.89		NEB2_HUMAN (1-824): 3.57e-44: 175: 45.39