HitPredict

Interactor 1: WIPF1 (O43516)
WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
Gene: WIPF1

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11331876
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0005522 - profilin binding GO:0005829 - cytosol GO:0005884 - actin filament
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 503 Hs			1 375
+	Hs
		554315 MUC1_HUMAN (3-456): 2.41e-21: 100: 14.19		ACTBL_HUMAN (2-375): 0: 734: 91.44
+	Hs
		1122431 SRCAP_HUMAN (2-497): 2.95e-09: 62.1: 12.65		ACTBL_HUMAN (2-375): 0: 734: 91.44
+	Hs
		891920 WIPF2_HUMAN (10-503): 6.61e-24: 105: 32.60		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		929941 WIPF2_HUMAN (10-503): 6.61e-24: 105: 32.60		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Rn
		892234 WIPF1_RAT (14-503): 3.4e-23: 104: 82.86		ACTB_RAT (1-375): 0: 604: 98.93
+	Hs
		932278 WIPF2_HUMAN (10-503): 6.61e-24: 105: 32.60		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		554290 MUC1_HUMAN (3-456): 2.41e-21: 100: 14.19		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		891853 SRCAP_HUMAN (2-497): 2.95e-09: 62.1: 12.65		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		929905 SRCAP_HUMAN (2-497): 2.95e-09: 62.1: 12.65		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		932219 SRCAP_HUMAN (2-497): 2.95e-09: 62.1: 12.65		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		932156 MDC1_HUMAN (2-496): 3.99e-09: 61.4: 13.74		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		203220 SYNJ1_HUMAN (2-362): 9.7e-09: 60.2: 13.72		ACTC_HUMAN (2-375): 0: 595: 94.39