HitPredict

Interactor 1: RRP46 (O42894)
Exosome complex component rrp46 (Ribosomal RNA-processing protein 46)
Gene: RRP46

Interactor 2: RRP43 (Q10205)
Exosome complex component rrp43 (Ribosomal RNA-processing protein 43)
Gene: RRP43

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23503588
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RNase_PH~RNase_PH, RNase_PH~RNase_PH_C
Common GO terms GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
and 12 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 226
Sp

1 270
+ Hs
+ Sp
+ At
+ Hs
+ At
+ Ss
+ At
+ Mt
+ Hs
+ Dm
+ At
+ Sp
+ Dm
+ Dm
+ At
+ Hs
+ At
+ Ec
+ Sp

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Last updated: 11Aug2025