HitPredict

Interactor 1: PRC1 (O43663)
Protein regulator of cytokinesis 1
Gene: PRC1

Interactor 2: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 221
+	Hs
		210020 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24
+	Hs
		209622 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		210240 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		SRSF8_HUMAN (1-183): 4.13e-29: 111: 63.39
+	Hs
		209954 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37
+	Hs
		210276 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		PABP3_HUMAN (15-221): 2.48e-24: 101: 16.91
+	Hs
		210352 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76
+	Hs
		210053 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		PAP1M_HUMAN (2-107): 2.44e-23: 94.3: 20.76
+	Hs
		210046 PRC1_HUMAN (1-620): 2.12e-153: 457: 100.00		PAP1L_HUMAN (104-193): 4.46e-11: 63.5: 8.89
+	Hs
		1073578 ITSN1_HUMAN (31-335): 2.15e-15: 82.4: 12.93		SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24