HitPredict

Interactor 1: AP1G1 (O43747)
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1 subunit gamma-1) (Adaptor-related protein complex 1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
Gene: AP1G1

Interactor 2: RABE1 (Q15276)
Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Gene: RABEP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	14665628, 14973137, 12042876, 12505986, 11387476, 10747088
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0016192 - vesicle-mediated transport GO:0043231 - intracellular membrane-bounded organelle GO:0055037 - recycling endosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 862
+	Hs
		276367 AP1G2_HUMAN (6-822): 0: 690: 58.02		RABE1_HUMAN (1-862): 6.85e-68: 244: 100.00
+	Hs
		321498 AP2A1_HUMAN (3-808): 0: 594: 24.39		MYH9_HUMAN (486-859): 1.31e-13: 77.4: 12.90
+	Hs
		148253 AP2A1_HUMAN (3-808): 0: 594: 24.39		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86
+	Hs
		148239 AP2A2_HUMAN (3-813): 0: 582: 24.55		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86
+	Hs
		724758 AP2B1_HUMAN (30-800): 0: 552: 16.59		MYH9_HUMAN (486-859): 1.31e-13: 77.4: 12.90
+	Hs
		148654 AP2B1_HUMAN (30-800): 0: 552: 16.59		CTRO_HUMAN (31-712): 1.44e-12: 74: 13.86