Interactor 1: RIPK2 (O43353)
Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)
Gene: RIPK2
Interactor 2: NOD2 (Q9HC29)
Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) (Inflammatory bowel disease protein 1)
Gene: NOD2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27812135, 15620648, 21123652, 26670046, 27545878, 11087742, 19592251, 22607974, 21097508, 16714539, 16552041, 16492792, 17054981, 19266573, 19464198, 19337385, 19667203, 24790089, 21931826, 35273242 and 1 others
more... |
| Identification Methods | affinity chromatography technology, fluorescent resonance energy transfer, two hybrid, anti tag coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD |
| Common GO terms | GO:0002250 - adaptive immune response GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton and 19 others more... |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
