HitPredict

Interactor 1: STRN (O43815)
Striatin
Gene: STRN

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.741

Property	Details
Experiments	18782753, 33961781, 26496610, 28330616, 35271311, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 780 Hs			1 309
+	Hs
		215211 STRN_HUMAN (1-780): 0: 650: 100.00		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		930823 STRN3_HUMAN (33-780): 0: 580: 63.56		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		915176 STRN3_HUMAN (33-780): 0: 580: 63.56		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Dm
		87967 D3DML3_DROME (40-780): 3.97e-129: 404: 42.57		PP2A_DROME (1-309): 0: 524: 93.85
+	Hs
		930873 Q59GV6_HUMAN (5-733): 2.04e-123: 389: 24.58		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		915209 Q59GV6_HUMAN (5-733): 2.04e-123: 389: 24.58		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		931012 STRN4_HUMAN (5-642): 2.34e-105: 341: 26.51		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		915286 STRN4_HUMAN (5-642): 2.34e-105: 341: 26.51		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		929393 RACK1_HUMAN (449-779): 4.95e-75: 247: 21.66		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		737729 RACK1_HUMAN (449-779): 4.95e-75: 247: 21.66		PP1G_HUMAN (7-306): 0: 505: 45.96
+	Zm
		32619 B6T9K7_MAIZE (332-642): 3.74e-59: 205: 11.73		A0A1D6KVM0_MAIZE (48-309): 2.73e-178: 499: 83.97
+	Hs
		108900 H0YJT2_HUMAN (227-441): 2.88e-34: 130: 42.27		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		108905 H0YJZ4_HUMAN (274-441): 2.6e-29: 115: 44.71		PP2AA_HUMAN (1-309): 0: 529: 100.00
+	Hs
		108904 H0YJZ4_HUMAN (274-441): 2.6e-29: 115: 44.71		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Hs
		737965 SNR40_HUMAN (508-779): 4.85e-16: 82.4: 25.54		PP1G_HUMAN (7-306): 0: 505: 45.96
+	Hs
		906069 SNR40_HUMAN (508-779): 4.85e-16: 82.4: 25.54		PP1A_HUMAN (5-296): 0: 504: 46.51