Interactor 1: ARK72 (O43488)
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) (Succinic semialdehyde reductase) (SSA reductase)
Gene: AKR7A2

Interactor 2: ARK73 (O95154)
Aldo-keto reductase family 7 member A3 (EC 1.1.1.2) (AFB1 aldehyde reductase 2) (AFB1-AR 2) (Aflatoxin B1 aldehyde reductase member 3)
Gene: AKR7A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 16189514, 32296183, 33961781, 38334954, 26186194, 28514442, 31515488, unassigned3799, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Aldo_ket_red~Aldo_ket_red
Common GO terms GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006081 - aldehyde metabolic process
GO:0009055 - electron transfer activity
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 359
Hs

1 331
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Last updated: 11Aug2025