HitPredict

Interactor 1: LDB2 (O43679)
LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1)
Gene: LDB2

Interactor 2: LHX3 (Q9UBR4)
LIM/homeobox protein Lhx3 (LIM homeobox protein 3)
Gene: LHX3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11882901
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	LID~LIM
Common GO terms	GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 373 Hs			1 397
+	Mm
		237317 LDB2_MOUSE (1-373): 0: 677: 97.59		LMX1B_MOUSE (1-339): 5.33e-63: 209: 28.50
+	Mm
		237322 LDB2_MOUSE (1-373): 0: 677: 97.59		LHX5_MOUSE (31-391): 6.67e-63: 209: 34.22
+	Mm
		237334 LDB2_MOUSE (1-373): 0: 677: 97.59		LMX1A_MOUSE (1-339): 2.57e-61: 204: 28.20
+	Mm
		237324 LDB2_MOUSE (1-373): 0: 677: 97.59		LHX1_MOUSE (31-396): 5.52e-58: 196: 33.01
+	Mm
		237337 LDB2_MOUSE (1-373): 0: 677: 97.59		LHX9_MOUSE (4-154): 1.92e-50: 176: 41.56
+	Hs
		223935 LDB2_HUMAN (1-373): 0: 677: 100.00		LMO3_HUMAN (31-159): 7.15e-52: 171: 41.05
+	Mm
		237327 LDB2_MOUSE (1-373): 0: 677: 97.59		LMO3_MOUSE (31-159): 7.15e-52: 171: 41.05
+	Mm
		237329 LDB2_MOUSE (1-373): 0: 677: 97.59		RBTN1_MOUSE (31-149): 2.36e-51: 171: 42.74
+	Hs
		223924 LDB2_HUMAN (1-373): 0: 677: 100.00		RBTN1_HUMAN (31-149): 5.44e-51: 170: 42.74
+	Hs
		223927 LDB2_HUMAN (1-373): 0: 677: 100.00		ISL1_HUMAN (21-321): 6.98e-49: 170: 28.57
+	Hs
		223931 LDB2_HUMAN (1-373): 0: 677: 100.00		LHX8_HUMAN (30-274): 8.37e-49: 170: 30.37
+	Mm
		237321 LDB2_MOUSE (1-373): 0: 677: 97.59		ISL1_MOUSE (21-321): 6.98e-49: 170: 28.57
+	Mm
		237330 LDB2_MOUSE (1-373): 0: 677: 97.59		ISL2_MOUSE (2-321): 3.48e-44: 158: 27.02
+	Hs
		253019 LDB1_HUMAN (8-373): 0: 610: 76.84		LMX1B_HUMAN (1-339): 7.04e-63: 209: 28.08
+	Hs
		223928 LDB2_HUMAN (1-373): 0: 677: 100.00		LMO4_HUMAN (31-148): 2.31e-28: 110: 43.09
+	Mm
		237323 LDB2_MOUSE (1-373): 0: 677: 97.59		LMO4_MOUSE (31-148): 2.31e-28: 110: 43.09
+	Hs
		682055 LDB1_HUMAN (8-373): 0: 610: 76.84		RBTN1_HUMAN (31-149): 5.44e-51: 170: 42.74
+	Mm
		237338 LDB2_MOUSE (1-373): 0: 677: 97.59		LHX2_MOUSE (136-281): 2.66e-15: 78.7: 23.90
+	Hs
		223938 LDB2_HUMAN (1-373): 0: 677: 100.00		LHX4_HUMAN (5-83): 1.56e-12: 70.4: 24.10
+	Mm
		237320 LDB2_MOUSE (1-373): 0: 677: 97.59		LHX4_MOUSE (5-83): 1.56e-12: 70.4: 24.10