HitPredict

Interactor 1: LDB2 (O55203)
LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1)
Gene: LDB2

Interactor 2: LMO4 (P61969)
LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)
Gene: LMO4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LID~LIM
Common GO terms	GO:0005634 - nucleus GO:0030334 - regulation of cell migration GO:0031252 - cell leading edge GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 373 Mm			1 165
+	Hs
		223931 LDB2_HUMAN (1-373): 0: 674: 97.59		LHX8_HUMAN (23-158): 3.97e-48: 160: 39.71
+	Mm
		237318 LDB2_MOUSE (1-373): 0: 677: 100.00		RBTN2_MOUSE (23-148): 4e-46: 149: 45.67
+	Hs
		223928 LDB2_HUMAN (1-373): 0: 674: 97.59		LMO4_HUMAN (1-165): 8.51e-43: 141: 100.00
+	Mm
		237321 LDB2_MOUSE (1-373): 0: 677: 100.00		ISL1_MOUSE (22-162): 8.36e-39: 136: 36.55
+	Mm
		237327 LDB2_MOUSE (1-373): 0: 677: 100.00		LMO3_MOUSE (13-152): 6.28e-41: 136: 47.86
+	Hs
		223927 LDB2_HUMAN (1-373): 0: 674: 97.59		ISL1_HUMAN (22-162): 8.36e-39: 136: 36.55
+	Hs
		223935 LDB2_HUMAN (1-373): 0: 674: 97.59		LMO3_HUMAN (13-152): 6.28e-41: 136: 47.86
+	Mm
		237329 LDB2_MOUSE (1-373): 0: 677: 100.00		RBTN1_MOUSE (1-143): 2.5e-35: 122: 48.25
+	Hs
		223923 LDB2_HUMAN (1-373): 0: 674: 97.59		RBTN2_HUMAN (23-140): 7.71e-36: 123: 46.61
+	Hs
		223924 LDB2_HUMAN (1-373): 0: 674: 97.59		RBTN1_HUMAN (1-143): 1.21e-35: 123: 48.25
+	Mm
		237320 LDB2_MOUSE (1-373): 0: 677: 100.00		LHX4_MOUSE (82-165): 1.03e-12: 66.6: 18.75
+	Hs
		223938 LDB2_HUMAN (1-373): 0: 674: 97.59		LHX4_HUMAN (82-165): 1.1e-12: 66.2: 18.75
+	Mm
		237322 LDB2_MOUSE (1-373): 0: 677: 100.00		LHX5_MOUSE (12-77): 3.62e-11: 62: 23.88
+	Mm
		237337 LDB2_MOUSE (1-373): 0: 677: 100.00		LHX9_MOUSE (87-165): 6.98e-11: 61.2: 17.39
+	Mm
		237317 LDB2_MOUSE (1-373): 0: 677: 100.00		LMX1B_MOUSE (12-80): 9.94e-11: 60.8: 30.00
+	Mm
		237334 LDB2_MOUSE (1-373): 0: 677: 100.00		LMX1A_MOUSE (12-82): 1.97e-10: 60.1: 29.17
+	Mm
		237324 LDB2_MOUSE (1-373): 0: 677: 100.00		LHX1_MOUSE (12-77): 6.23e-10: 58.5: 23.88
+	Mm
		237338 LDB2_MOUSE (1-373): 0: 677: 100.00		LHX2_MOUSE (15-85): 1.11e-09: 57.7: 25.00
+	Mm
		237330 LDB2_MOUSE (1-373): 0: 677: 100.00		ISL2_MOUSE (76-165): 3.06e-09: 56.6: 13.73
+	Hs
		223951 LDB2_HUMAN (1-373): 0: 674: 97.59		LHX3_HUMAN (14-78): 6.67e-10: 58.5: 22.73