HitPredict

Interactor 1: MED14 (O60244)
Mediator of RNA polymerase II transcription subunit 14 (Activator-recruited cofactor 150 kDa component) (ARC150) (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (RGR1 homolog) (hRGR1) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150)
Gene: MED14

Interactor 2: RPB9 (P36954)
DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5)
Gene: POLR2I

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1454 Hs			1 125
+	Hs
		123867 SPT5H_HUMAN (1062-1272): 9.25e-11: 68.8: 14.41		RPB9_HUMAN (1-125): 3.43e-55: 169: 100.00
+	Bt
		102292 RPB1_BOVIN (1059-1159): 8.45e-09: 62.5: 23.30		RPB9_BOVIN (1-125): 3e-55: 170: 99.20
+	Hs
		624795 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		RPB9_HUMAN (1-125): 3.43e-55: 169: 100.00
+	Dm
		375646 RPB1_DROME (1020-1358): 1.57e-09: 64.9: 10.10		RPB9_DROME (6-125): 1.36e-51: 161: 77.50
+	Hs
		1144643 TENS2_HUMAN (905-1243): 1.16e-17: 91.8: 14.14		RPA12_HUMAN (12-125): 2.72e-23: 89: 16.67
+	Hs
		625076 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		RPA12_HUMAN (12-125): 2.72e-23: 89: 16.67
+	Hs
		612955 RPB1_HUMAN (1059-1159): 8.88e-09: 62.5: 23.30		TCEA1_HUMAN (57-124): 4.63e-15: 70.9: 23.53