Protein: ERD23
ER lumen protein-retaining receptor 3 (KDEL endoplasmic reticulum protein retention receptor 3) (KDEL receptor 3)

Gene: ERD23, KDELR3
Organism: Homo sapiens
Interactions: 51
UniProt ID: O43731

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005046 - KDEL sequence binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005801 - cis-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225393

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

0

High-throughput

0.660

High

225371

MBOA5
Lysophospholipid acyltransferase 5

2

1

High-throughput

0.628

High

225377

SPP2B
Signal peptide peptidase-like 2B

2

1

High-throughput

0.628

High

225391

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

2

3

High-throughput

0.628

High

225349

TSN2
Tetraspanin-2

3

1

High-throughput

0.607

High

225384

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.602

High

225387

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

2

0

High-throughput

0.602

High

225364

LPAR6
Lysophosphatidic acid receptor 6

2

8

High-throughput

0.558

High

225354

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

2

High-throughput

0.536

High

225379

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

5

High-throughput

0.536

High

225385

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

1

High-throughput

0.536

High

225368

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.513

High

225370

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

49721

TMM72
Transmembrane protein 72

1

1

High-throughput

0.489

High

165868

FFAR1
Free fatty acid receptor 1

1

10

High-throughput

0.489

High

182422

GP182
G-protein coupled receptor 182

1

7

High-throughput

0.489

High

225350

TM63A
Mechanosensitive cation channel TMEM63A

1

1

High-throughput

0.489

High

225351

S1PR4
Sphingosine 1-phosphate receptor 4

1

7

High-throughput

0.489

High

225357

FPR2
N-formyl peptide receptor 2

1

5

High-throughput

0.489

High

225359

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

4

High-throughput

0.489

High

225361

GPV
Platelet glycoprotein V

1

1

High-throughput

0.489

High

225362

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

4

High-throughput

0.489

High

225363

EAA3
Excitatory amino acid transporter 3

1

1

High-throughput

0.489

High

225369

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

8

High-throughput

0.489

High

225373

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

8

High-throughput

0.489

High

225374

S22A9
Organic anion transporter 7

1

2

High-throughput

0.489

High

225386

OPALI
Opalin

1

2

High-throughput

0.489

High

225388

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.489

High

225390

LPAR2
Lysophosphatidic acid receptor 2

1

7

High-throughput

0.489

High

225394

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.489

High

217558

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

225356

ERD21
ER lumen protein-retaining receptor 1

1

4

High-throughput

0.479

High

225360

ERD22
ER lumen protein-retaining receptor 2

1

4

High-throughput

0.479

High

225392

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

Small-scale

0.479

High

225355

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.445

High

225365

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.437

High

225382

BSCL2
Seipin

1

0

High-throughput

0.426

High

225367

CXCR4
C-X-C chemokine receptor type 4

1

6

High-throughput

0.407

High

225352

B3A2
Anion exchange protein 2

2

0

High-throughput

0.328

High

225378

TM171
Transmembrane protein 171

2

0

High-throughput

0.318

High

225389

DPEP2
Dipeptidase 2

2

0

High-throughput

0.318

High

62860

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.279

Low

225353

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

225358

LCN1
Lipocalin-1

1

0

High-throughput

0.279

Low

225366

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.279

Low

225375

NNRD
ATP-dependent

1

0

High-throughput

0.279

Low

225376

PCD20
Protocadherin-20

1

0

High-throughput

0.279

Low

225380

INT12
Integrator complex subunit 12

1

0

High-throughput

0.279

Low

225383

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.279

Low

225372

S39A4
Zinc transporter ZIP4

1

0

High-throughput

0.249

Low

225381

NTCP4
Sodium/bile acid cotransporter 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025