Interactor 1: KPRB (O60256)
Phosphoribosyl pyrophosphate synthase-associated protein 2 (PRPP synthase-associated protein 2) (41 kDa phosphoribosypyrophosphate synthetase-associated protein) (PAP41)
Gene: PRPSAP2
Interactor 2: PRPS2 (P11908)
Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (PPRibP) (Phosphoribosyl pyrophosphate synthase II) (PRS-II)
Gene: PRPS2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.926 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 32296183, 33961781, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pribosyl_synth~Pribosyl_synth, Pribosyl_synth~Pribosyltran_N, Pribosyltran_N~Pribosyltran_N |
| Common GO terms | GO:0000287 - magnesium ion binding GO:0002189 - ribose phosphate diphosphokinase complex GO:0004749 - ribose phosphate diphosphokinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm and 3 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
