HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: GORS2 (Q9H8Y8)
Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59)
Gene: GORASP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 452
+	Hs
		229228 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PCLO_HUMAN (176-452): 1.1e-10: 66.5: 14.01
+	Hs
		228101 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KMT2C_HUMAN (130-449): 2.01e-09: 62.2: 13.35
+	Mm
		88466 PRKN_MOUSE (1-465): 6.53e-131: 388: 83.66		D3Z656_MOUSE (179-450): 3.7e-10: 64.5: 16.96
+	At
		1091778 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		SC31B_ARATH (217-443): 9.47e-21: 97.7: 14.54
+	Hs
		475943 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		OTOG_HUMAN (173-436): 4.9e-11: 67.2: 12.89
+	At
		1092229 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		SC24C_ARATH (247-450): 1.4e-09: 62.6: 12.89
+	At
		1092118 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		Q9LIE8_ARATH (204-452): 8.08e-09: 60.3: 15.77