HitPredict

Interactor 1: PEPL (O60437)
Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)
Gene: PPL

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31586073, 36526897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1756 Hs			1 1124
+	Hs
		1068674 PLEC_HUMAN (1-1360): 9.93e-42: 171: 10.15		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		728519 MYH11_HUMAN (1-836): 1.44e-34: 147: 9.73		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		725034 MYH9_HUMAN (772-1656): 1.06e-32: 141: 16.74		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		502927 MYH3_HUMAN (4-887): 4.28e-29: 129: 9.04		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1045536 SPTN1_HUMAN (4-1191): 1.92e-18: 94.9: 10.52		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1061260 NUMA1_HUMAN (2-783): 1.46e-15: 85.3: 10.87		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1059276 GOGB1_HUMAN (1144-1736): 3.26e-14: 81: 12.80		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		506845 SPTB1_HUMAN (189-1505): 5e-14: 80.3: 10.93		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		551849 DESP_HUMAN (1031-1718): 1.69e-13: 78.7: 12.03		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		164668 SPTN2_HUMAN (73-1521): 7.79e-13: 76.4: 12.03		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1343798 MACF1_HUMAN (498-1680): 1.71e-12: 75.4: 12.90		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1268098 MY18A_HUMAN (485-984): 1.11e-10: 69.2: 12.86		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		963430 SPTB2_HUMAN (559-1683): 4.02e-10: 67.6: 11.36		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1271312 EVPL_HUMAN (2-640): 2.11e-09: 64.9: 7.68		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		974153 DYST_HUMAN (724-1629): 8.16e-09: 63.1: 11.55		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		1303384 MYSN_DROME (595-1444): 1e-10: 69.3: 22.10		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84