HitPredict

Interactor 1: CCNT1 (O60563)
Cyclin-T1 (CycT1) (Cyclin-T)
Gene: CCNT1

Interactor 2: CDK14 (O94921)
Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)
Gene: CDK14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cyclin_N~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 726 Hs			1 469
+	Hs
		236679 CCNT1_HUMAN (1-715): 0: 591: 100.00		CDK1_HUMAN (132-422): 3.66e-130: 380: 48.30
+	Hs
		625350 CCNA1_HUMAN (4-273): 9.89e-86: 280: 16.24		CDK2_HUMAN (132-429): 1.34e-141: 409: 50.67
+	Zm
		11296 A0A1D6JBU3_MAIZE (3-475): 3.34e-91: 295: 22.77		A0A1D6FC67_MAIZE (75-462): 8.33e-128: 378: 25.06
+	Mm
		956329 CCNA1_MOUSE (4-274): 4.65e-86: 279: 16.54		CDK2_MOUSE (132-429): 1.63e-132: 388: 43.97
+	Hs
		414855 CCNA1_HUMAN (4-273): 9.89e-86: 280: 16.24		CDK1_HUMAN (132-422): 3.66e-130: 380: 48.30
+	Hs
		538471 CCNB1_HUMAN (4-281): 4e-75: 250: 12.95		CDK2_HUMAN (132-429): 1.34e-141: 409: 50.67
+	Hs
		538521 CCNB1_HUMAN (4-281): 4e-75: 250: 12.95		CDK3_HUMAN (132-442): 4.46e-138: 400: 50.48
+	At
		621697 CCA31_ARATH (1-274): 9.12e-80: 260: 13.17		CDKA1_ARATH (132-423): 7.17e-131: 381: 50.34
+	Hs
		841352 CCNL1_HUMAN (9-523): 6.46e-79: 264: 17.89		CDK7_HUMAN (129-467): 2.78e-128: 377: 37.61
+	At
		1247203 CCL11_ARATH (6-408): 2.47e-76: 253: 20.95		Q9CAG1_ARATH (54-451): 6.51e-127: 387: 32.84
+	At
		621661 CCB12_ARATH (4-273): 6.27e-77: 256: 13.33		CDKA1_ARATH (132-423): 7.17e-131: 381: 50.34
+	At
		621662 CCA21_ARATH (16-276): 1.32e-75: 252: 12.41		CDKA1_ARATH (132-423): 7.17e-131: 381: 50.34
+	Hs
		538522 CCNB1_HUMAN (4-281): 4e-75: 250: 12.95		CDK5_HUMAN (132-425): 1.23e-130: 381: 52.70
+	Hs
		414711 CCNB1_HUMAN (4-281): 4e-75: 250: 12.95		CDK1_HUMAN (132-422): 3.66e-130: 380: 48.30
+	Dm
		618404 Q961D1_DROME (9-334): 1.69e-76: 253: 25.52		CDK1_DROME (132-422): 1.35e-128: 376: 45.58
+	Dm
		618463 Q961D1_DROME (9-334): 1.69e-76: 253: 25.52		CDK2_DROME (130-422): 2.48e-128: 376: 47.62
+	Hs
		538497 CCNB1_HUMAN (4-281): 4e-75: 250: 12.95		CDK7_HUMAN (129-467): 2.78e-128: 377: 37.61
+	Mm
		509465 CCNB1_MOUSE (4-268): 4.73e-75: 250: 14.61		CDK1_MOUSE (132-422): 1.13e-128: 376: 48.30
+	Dm
		540472 CCNA_DROME (4-304): 9.42e-74: 249: 14.90		CDK1_DROME (132-422): 1.35e-128: 376: 45.58
+	Ca
		793055 CG11_CANAL (26-617): 1.59e-72: 250: 11.91		CDK1_CANAL (131-419): 1.46e-127: 374: 51.02