HitPredict

Interactor 1: KLK8 (O60259)
Kallikrein-8 (hK8) (EC 3.4.21.118) (Neuropsin) (NP) (Ovasin) (Serine protease 19) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein)
Gene: KLK8

Interactor 2: ORNT1 (Q9Y619)
Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15)
Gene: SLC25A15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 260 Hs			1 301
+	Hs
		449632 KLK1_HUMAN (12-259): 1.3e-106: 310: 41.09		ORNT1_HUMAN (1-301): 2.1e-90: 272: 100.00
+	Hs
		240179 KLK8_HUMAN (1-260): 2.56e-126: 360: 100.00		ADT1_HUMAN (100-301): 9.26e-41: 145: 20.57
+	Hs
		449590 KLK1_HUMAN (12-259): 1.3e-106: 310: 41.09		ADT1_HUMAN (100-301): 9.26e-41: 145: 20.57
+	Hs
		437707 HEPS_HUMAN (15-257): 3.9e-95: 287: 31.32		SCMC1_HUMAN (94-298): 2.62e-47: 166: 17.07
+	Hs
		552338 KLK6_HUMAN (10-259): 3.09e-103: 301: 45.42		ADT3_HUMAN (101-301): 4.44e-40: 143: 20.67
+	Hs
		552439 KLK9_HUMAN (30-258): 1.16e-100: 295: 48.05		ADT3_HUMAN (101-301): 4.44e-40: 143: 20.67
+	Hs
		1448850 TMPS4_HUMAN (6-259): 8.21e-95: 287: 31.46		S2513_HUMAN (109-300): 2.03e-38: 145: 23.44
+	Hs
		552084 TMPS4_HUMAN (6-259): 8.21e-95: 287: 31.46		ADT1_HUMAN (100-301): 9.26e-41: 145: 20.57
+	Hs
		552169 KLK7_HUMAN (24-258): 5.36e-98: 288: 46.19		ADT3_HUMAN (101-301): 4.44e-40: 143: 20.67
+	Mm
		399227 CFAD_MOUSE (15-255): 5.99e-45: 153: 38.65		ORNT1_MOUSE (1-301): 2.65e-91: 275: 95.02
+	Hs
		210796 KLK10_HUMAN (36-259): 3.32e-91: 272: 45.85		S2513_HUMAN (109-300): 2.03e-38: 145: 23.44
+	Hs
		210695 KLK10_HUMAN (36-259): 3.32e-91: 272: 45.85		ADT3_HUMAN (101-301): 4.44e-40: 143: 20.67
+	Hs
		227014 KLK1_HUMAN (12-259): 1.3e-106: 310: 41.09		MCAT_HUMAN (204-299): 5.02e-18: 84.1: 27.72
+	Hs
		227029 KLK15_HUMAN (23-259): 8.53e-101: 295: 45.57		MCAT_HUMAN (204-299): 5.02e-18: 84.1: 27.72
+	Hs
		1235755 KLK5_HUMAN (24-259): 4.61e-98: 290: 47.48		SCMC2_HUMAN (209-299): 1.21e-17: 84.4: 21.98
+	Mm
		398645 CFAD_MOUSE (15-255): 5.99e-45: 153: 38.65		SCMC1_MOUSE (94-298): 2.76e-46: 163: 18.05
+	Mm
		398171 CFAD_MOUSE (15-255): 5.99e-45: 153: 38.65		ADT1_MOUSE (100-301): 3.07e-41: 146: 20.57
+	Mm
		398180 CFAD_MOUSE (15-255): 5.99e-45: 153: 38.65		ADT2_MOUSE (101-301): 9.06e-41: 145: 20.67
+	Mm
		398616 CFAD_MOUSE (15-255): 5.99e-45: 153: 38.65		S2512_MOUSE (213-300): 7.33e-21: 94.5: 25.53
+	Mm
		399255 CFAD_MOUSE (15-255): 5.99e-45: 153: 38.65		MCAT_MOUSE (204-299): 1.51e-18: 85.6: 27.72