HitPredict

Interactor 1: HPGDS (O60760)
Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase)
Gene: HPGDS

Interactor 2: HPGDS (O60760)
Hematopoietic prostaglandin D synthase (H-PGDS) (EC 5.3.99.2) (GST class-sigma) (Glutathione S-transferase) (EC 2.5.1.18) (Glutathione-dependent PGD synthase) (Glutathione-requiring prostaglandin D synthase) (Prostaglandin-H2 D-isomerase)
Gene: HPGDS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.712

The method score is based on:

Property Details
Experiments 22418579, 18341273
Identification Methods x-ray crystallography
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains GST_C_3~GST_C_3, GST_C_3~GST_N, GST_N~GST_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0001516 - prostaglandin biosynthetic process
GO:0004364 - glutathione transferase activity
GO:0004667 - prostaglandin-D synthase activity
GO:0005509 - calcium ion binding
and 10 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 199
Hs

1 199
+ Dm
+ Dm
+ Hs
+ Ce
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024