Protein: PRAF3
PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Cytoskeleton-related vitamin A-responsive protein) (Dermal papilla-derived protein 11) (GTRAP3-18) (Glutamate transporter EAAC1-interacting protein) (JM5) (Prenylated Rab acceptor protein 2) (Protein JWa) (Putative MAPK-activating protein PM27)

Gene: PRAF3, ARL6IP5
Organism: Homo sapiens
Interactions: 179
UniProt ID: O75915

Gene Ontology (top 5):
GO:0002037 - negative regulation of L-glutamate import across plasma membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0006749 - glutathione metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

277763

RTN4
Reticulon-4

4

10

High-throughput

0.699

High

61232

5HT3E
5-hydroxytryptamine receptor 3E

3

1

High-throughput

0.667

High

277715

RETR3
Reticulophagy regulator 3

3

2

High-throughput

0.667

High

242210

PRAF2
PRA1 family protein 2

3

5

Small-scale

0.650

High

277639

ICAM2
Intercellular adhesion molecule 2

3

0

High-throughput

0.638

High

277676

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

3

0

High-throughput

0.638

High

277738

RN185
E3 ubiquitin-protein ligase RNF185

2

2

Small-scale

0.631

High

237704

TSN2
Tetraspanin-2

2

4

High-throughput

0.628

High

277624

S1PR2
Sphingosine 1-phosphate receptor 2

2

6

High-throughput

0.628

High

277649

FPR2
N-formyl peptide receptor 2

2

3

High-throughput

0.628

High

277650

NK1R
Substance-P receptor

2

1

High-throughput

0.628

High

277658

VIPR1
Vasoactive intestinal polypeptide receptor 1

2

1

High-throughput

0.628

High

277772

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

6

High-throughput

0.628

High

277629

RASK
GTPase KRas

2

6

High-throughput

0.614

High

277666

LPAR6
Lysophosphatidic acid receptor 6

2

3

High-throughput

0.611

High

277694

IFM3
Interferon-induced transmembrane protein 3

2

2

High-throughput

0.611

High

277712

TM11B
Transmembrane protease serine 11B

2

2

High-throughput

0.611

High

277748

ESYT1
Extended synaptotagmin-1

2

3

High-throughput

0.611

High

277750

DERL1
Derlin-1

2

2

High-throughput

0.611

High

277756

P2Y12
P2Y purinoceptor 12

2

4

High-throughput

0.611

High

277635

GLPB
Glycophorin-B

2

0

High-throughput

0.602

High

277647

EVI2A
Protein EVI2A

2

0

High-throughput

0.585

High

277671

RAB7A
Ras-related protein Rab-7a

2

9

Small-scale

0.584

High

277677

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.584

High

277693

REEP5
Receptor expression-enhancing protein 5

2

8

High-throughput

0.558

High

277663

CCR2
C-C chemokine receptor type 2

1

4

High-throughput

0.541

High

277664

EAA3
Excitatory amino acid transporter 3

1

0

Small-scale

0.537

High

50290

TSN11
Tetraspanin-11

1

5

High-throughput

0.536

High

118938

KCNK1
Potassium channel subfamily K member 1

1

1

High-throughput

0.536

High

125948

UPK1A
Uroplakin-1a

1

6

High-throughput

0.536

High

134347

ACKR2
Atypical chemokine receptor 2

1

4

High-throughput

0.536

High

149501

COPE
Coatomer subunit epsilon

1

1

High-throughput

0.536

High

157796

T4S5
Transmembrane 4 L6 family member 5

1

1

High-throughput

0.536

High

277625

RTN3
Reticulon-3

1

10

High-throughput

0.536

High

277626

TSN15
Tetraspanin-15

1

4

High-throughput

0.536

High

277627

S1PR4
Sphingosine 1-phosphate receptor 4

1

6

High-throughput

0.536

High

277637

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

277646

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

5

High-throughput

0.536

High

277652

1433T
14-3-3 protein theta

1

5

High-throughput

0.536

High

277657

1433B
14-3-3 protein beta/alpha

1

5

High-throughput

0.536

High

277659

CNR2
Cannabinoid receptor 2

1

5

Small-scale

0.536

High

277661

DHB2
17-beta-hydroxysteroid dehydrogenase type 2

1

1

High-throughput

0.536

High

277683

COPZ1
Coatomer subunit zeta-1

1

1

High-throughput

0.536

High

277685

1433G
14-3-3 protein gamma

1

5

High-throughput

0.536

High

277696

1433F
14-3-3 protein eta

1

5

High-throughput

0.536

High

277699

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

1

High-throughput

0.536

High

277701

MOG
Myelin-oligodendrocyte glycoprotein

1

1

High-throughput

0.536

High

277705

RTN1
Reticulon-1

1

10

High-throughput

0.536

High

277718

F241A
Uncharacterized protein FAM241A

1

1

High-throughput

0.536

High

277719

ZDH22
Palmitoyltransferase ZDHHC22

1

1

High-throughput

0.536

High

277724

ATLA2
Atlastin-2

1

1

High-throughput

0.536

High

277728

LPAR1
Lysophosphatidic acid receptor 1

1

5

High-throughput

0.536

High

277731

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

5

High-throughput

0.536

High

277736

F241B
Protein FAM241B

1

1

High-throughput

0.536

High

277737

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

2

High-throughput

0.536

High

277751

TX101
Testis-expressed protein 101

1

2

High-throughput

0.536

High

277753

DERL2
Derlin-2

1

2

High-throughput

0.536

High

277758

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

1

High-throughput

0.536

High

277761

LPAR2
Lysophosphatidic acid receptor 2

1

6

High-throughput

0.536

High

277779

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

1

High-throughput

0.536

High

270546

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.518

High

277667

NOTC1
Neurogenic locus notch homolog protein 1

1

0

High-throughput

0.518

High

170010

PLS1
Phospholipid scramblase 1

1

0

High-throughput

0.513

High

277655

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.513

High

277662

GPV
Platelet glycoprotein V

1

0

High-throughput

0.513

High

277675

EFNA4
Ephrin-A4

1

0

High-throughput

0.513

High

277680

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

277686

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.513

High

277726

T170A
Transmembrane protein 170A

1

0

High-throughput

0.513

High

277733

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

277735

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.513

High

277742

TECTB
Beta-tectorin

1

0

High-throughput

0.513

High

277745

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.513

High

277746

PRRT1
Proline-rich transmembrane protein 1

1

0

High-throughput

0.513

High

277749

TMM43
Transmembrane protein 43

1

0

High-throughput

0.513

High

277768

GP173
Probable G-protein coupled receptor 173

1

0

High-throughput

0.513

High

277774

COPG2
Coatomer subunit gamma-2

1

0

High-throughput

0.513

High

277684

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

High-throughput

0.493

High

168690

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

2

High-throughput

0.489

High

277691

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.489

High

277695

LMNB2
Lamin-B2

1

5

High-throughput

0.489

High

277730

ARC1A
Actin-related protein 2/3 complex subunit 1A

1

2

High-throughput

0.489

High

277754

ARL6
ADP-ribosylation factor-like protein 6

1

6

Small-scale

0.481

High

48206

ESYT2
Extended synaptotagmin-2

1

3

High-throughput

0.479

High

120247

RHOD
Rho-related GTP-binding protein RhoD

1

9

High-throughput

0.479

High

163690

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.479

High

177756

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

277628

RASN
GTPase NRas

1

7

High-throughput

0.479

High

277632

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

277633

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

277636

RHOC
Rho-related GTP-binding protein RhoC

1

7

High-throughput

0.479

High

277638

UBL4A
Ubiquitin-like protein 4A

1

1

High-throughput

0.479

High

277640

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

277644

ATP4A
Potassium-transporting ATPase alpha chain 1

1

4

Small-scale

0.479

High

277645

LMNB1
Lamin-B1

1

5

High-throughput

0.479

High

277654

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

277670

RAB5C
Ras-related protein Rab-5C

1

9

High-throughput

0.479

High

277672

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

277673

CCR5
C-C chemokine receptor type 5

1

4

Small-scale

0.479

High

277674

RND2
Rho-related GTP-binding protein RhoN

1

13

High-throughput

0.479

High

277678

RAC3
Ras-related C3 botulinum toxin substrate 3

1

5

High-throughput

0.479

High

277679

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

277682

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

277687

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.479

High

277688

RHOB
Rho-related GTP-binding protein RhoB

1

8

High-throughput

0.479

High

277690

RAC1
Ras-related C3 botulinum toxin substrate 1

1

5

High-throughput

0.479

High

277697

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

277700

RHOH
Rho-related GTP-binding protein RhoH

1

11

High-throughput

0.479

High

277707

TM128
Transmembrane protein 128

1

3

High-throughput

0.479

High

277709

TECT3
Tectonic-3

1

3

High-throughput

0.479

High

277710

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

277714

PAQR2
Adiponectin receptor protein 2

1

1

Small-scale

0.479

High

277717

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

277727

5HT3C
5-hydroxytryptamine receptor 3C

1

1

High-throughput

0.479

High

277732

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

277739

TECT2
Tectonic-2

1

3

High-throughput

0.479

High

277740

DNJC1
DnaJ homolog subfamily C member 1

1

1

High-throughput

0.479

High

277744

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

277752

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.479

High

277757

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.479

High

277760

RHOF
Rho-related GTP-binding protein RhoF

1

9

High-throughput

0.479

High

277767

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

277770

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

277773

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

277777

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

277778

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

48981

SHOT1
Shootin-1

1

1

High-throughput

0.470

High

277764

MID51
Mitochondrial dynamics protein MIEF1

1

2

High-throughput

0.470

High

277747

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.460

High

277775

CLN8
Protein CLN8

1

0

Small-scale

0.460

High

274458

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

277631

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

277651

DDX6
Probable ATP-dependent RNA helicase DDX6

1

0

High-throughput

0.458

High

277665

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

277669

EMD
Emerin

1

0

High-throughput

0.458

High

277689

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.458

High

277703

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

277706

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.458

High

277711

GAK6
Endogenous retrovirus group K member 6 Gag polyprotein

1

0

High-throughput

0.458

High

277713

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

0

High-throughput

0.458

High

277722

T185A
Transmembrane protein 185A

1

0

High-throughput

0.458

High

277723

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

277725

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.458

High

277734

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

277755

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.458

High

277759

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

277765

NPDC1
Neural proliferation differentiation and control protein 1

1

0

High-throughput

0.458

High

277766

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

277771

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

81596

B7Z3K1
cDNA FLJ51973

1

3

High-throughput

0.445

High

277630

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

5

High-throughput

0.437

High

277641

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

277653

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

277660

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

277692

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

277720

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.437

High

277729

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

277721

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

277634

ISG15
Ubiquitin-like protein ISG15

1

1

Small-scale

0.407

High

168861

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.279

Low

277648

H2B1O
Histone H2B type 1-O

1

0

High-throughput

0.279

Low

277656

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

277716

S22A9
Organic anion transporter 7

1

0

High-throughput

0.279

Low

277762

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.279

Low

734

MEIKN
Meiosis-specific kinetochore protein

1

0

High-throughput

0.269

Low

277698

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.269

Low

277704

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.269

Low

126491

LORF2
LINE-1 retrotransposable element ORF2 protein

1

0

High-throughput

0.249

Low

277623

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.249

Low

277642

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.249

Low

277643

XRCC1
DNA repair protein XRCC1

1

0

Small-scale

0.249

Low

277668

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.249

Low

277681

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.249

Low

277702

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

277708

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

277741

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.249

Low

277743

MINT
Msx2-interacting protein

1

0

High-throughput

0.249

Low

277769

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

277776

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024