HitPredict

Interactor 1: DKC1 (O60832)
H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)
Gene: DKC1

Interactor 2: SHQ1 (Q6PI26)
Protein SHQ1 homolog
Gene: SHQ1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 25553844, 26186194, 28514442, 33961781, 22085966, 29178645
Identification Methods x-ray crystallography, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PUA~SHQ1
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:1904874 - positive regulation of telomerase RNA localization to Cajal body
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 514
Hs

1 577
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024