HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0008284 - positive regulation of cell population proliferation GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 822
+	Hs
		507875 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Hs
		508145 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Hs
		243293 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		FGFR4_HUMAN (29-808): 0: 664: 55.60
+	Hs
		609471 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR3_HUMAN (6-821): 0: 730: 61.22
+	Hs
		608081 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FGFR4_HUMAN (29-808): 0: 664: 55.60
+	Hs
		608166 DJB11_HUMAN (2-355): 1.66e-108: 325: 35.85		FGFR4_HUMAN (29-808): 0: 664: 55.60
+	Hs
		243425 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08
+	Hs
		243305 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		UFO_HUMAN (8-815): 1.07e-155: 479: 21.98
+	Hs
		681463 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08
+	Hs
		674347 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		UFO_HUMAN (8-815): 1.07e-155: 479: 21.98
+	Hs
		243251 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96
+	Hs
		384352 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96
+	Hs
		1081563 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08
+	Hs
		243261 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		RET_HUMAN (384-774): 2.63e-98: 332: 45.77
+	Hs
		385330 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96
+	Hs
		385658 DJB11_HUMAN (2-355): 1.66e-108: 325: 35.85		NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96
+	Hs
		434302 DJB11_HUMAN (2-355): 1.66e-108: 325: 35.85		RET_HUMAN (384-774): 2.63e-98: 332: 45.77
+	Hs
		738254 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FLT3_HUMAN (462-754): 8.76e-79: 276: 43.47
+	Hs
		681349 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15
+	Hs
		729333 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15