HitPredict

Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22412018
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031507 - heterochromatin formation GO:0035861 - site of double-strand break
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1052 Hs			1 664
+	Hs
		566367 CHD3_HUMAN (24-1052): 0: 807: 27.31		K2C5_HUMAN (24-390): 2e-117: 365: 25.95
+	Hs
		876463 CHD3_HUMAN (24-1052): 0: 807: 27.31		K2C6C_HUMAN (24-407): 2.37e-116: 361: 24.03
+	Hs
		385266 CHD3_HUMAN (24-1052): 0: 807: 27.31		K2C6A_HUMAN (23-407): 4.96e-116: 360: 23.71
+	Hs
		407282 CHD3_HUMAN (24-1052): 0: 807: 27.31		K2C6B_HUMAN (24-407): 4.84e-115: 357: 23.51
+	Hs
		566380 CHD4_HUMAN (24-945): 0: 792: 27.67		K2C5_HUMAN (24-390): 2e-117: 365: 25.95
+	Hs
		876470 CHD4_HUMAN (24-945): 0: 792: 27.67		K2C6C_HUMAN (24-407): 2.37e-116: 361: 24.03
+	Hs
		385272 CHD4_HUMAN (24-945): 0: 792: 27.67		K2C6A_HUMAN (23-407): 4.96e-116: 360: 23.71
+	Hs
		407291 CHD4_HUMAN (24-945): 0: 792: 27.67		K2C6B_HUMAN (24-407): 4.84e-115: 357: 23.51
+	Hs
		386258 CHD8_HUMAN (6-1031): 0: 812: 26.37		LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00
+	Hs
		385691 CHD3_HUMAN (24-1052): 0: 807: 27.31		LMNA_HUMAN (1-664): 1.26e-79: 267: 100.00
+	Hs
		634420 CHD3_HUMAN (24-1052): 0: 807: 27.31		LMNB1_HUMAN (21-581): 1.2e-49: 184: 54.45
+	Hs
		634446 CHD4_HUMAN (24-945): 0: 792: 27.67		LMNB1_HUMAN (21-581): 1.2e-49: 184: 54.45
+	Hs
		1127786 CHD4_HUMAN (24-945): 0: 792: 27.67		K1H2_HUMAN (30-387): 2.71e-44: 166: 23.18
+	Hs
		474640 CHD3_HUMAN (24-1052): 0: 807: 27.31		VIME_HUMAN (27-389): 3.96e-31: 129: 28.93
+	Hs
		451149 CHD3_HUMAN (24-1052): 0: 807: 27.31		NFL_HUMAN (28-433): 1.97e-26: 115: 27.07
+	Hs
		474680 CHD4_HUMAN (24-945): 0: 792: 27.67		VIME_HUMAN (27-389): 3.96e-31: 129: 28.93
+	Hs
		1088575 CHD3_HUMAN (24-1052): 0: 807: 27.31		KRT84_HUMAN (235-556): 2.85e-11: 68.7: 12.04
+	Hs
		1133001 CHD4_HUMAN (24-945): 0: 792: 27.67		KRT84_HUMAN (235-556): 2.85e-11: 68.7: 12.04
+	Hs
		1007474 CHD4_HUMAN (24-945): 0: 792: 27.67		KRT83_HUMAN (250-559): 1.08e-10: 66.4: 13.13
+	Hs
		1132806 CHD4_HUMAN (24-945): 0: 792: 27.67		K2C73_HUMAN (226-558): 7.25e-09: 60.6: 11.63