HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: TCEA1 (P23193)
Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o)
Gene: TCEA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32416067, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 301
+	Hs
		244717 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		PHF3_HUMAN (1-250): 1.13e-52: 187: 22.73
+	Hs
		244869 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		DIDO1_HUMAN (89-247): 2.35e-34: 134: 23.93
+	Hs
		243747 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MED26_HUMAN (7-142): 2.85e-23: 101: 24.09
+	Sc
		425492 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		TFS2_YEAST (3-300): 8.07e-76: 235: 31.85
+	Sc
		425465 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		TFS2_YEAST (3-300): 8.07e-76: 235: 31.85
+	Hs
		313395 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		MED26_HUMAN (7-142): 2.85e-23: 101: 24.09