Protein: ARGAL
Rho guanine nucleotide exchange factor 10-like protein (GrinchGEF)

Gene: ARGAL, ARHGEF10L
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9HCE6

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0030036 - actin cytoskeleton organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

174272

ARHGA
Rho guanine nucleotide exchange factor 10

3

16

High-throughput

0.839

High

1279850

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

2

8

High-throughput

0.737

High

1438966

FEM1B
Protein fem-1 homolog B

1

13

High-throughput

0.691

High

1340814

COP1
E3 ubiquitin-protein ligase COP1

2

9

High-throughput

0.601

High

1438960

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

15

High-throughput

0.575

High

987222

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

6

High-throughput

0.571

High

1122169

UBP2L
Ubiquitin-associated protein 2-like

2

4

High-throughput

0.571

High

1438968

DD19B
ATP-dependent RNA helicase DDX19B

2

6

High-throughput

0.571

High

873323

COPD
Coatomer subunit delta

2

0

High-throughput

0.547

High

133691

WASL
Actin nucleation-promoting factor WASL

1

7

High-throughput

0.536

High

733440

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

1144173

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1438967

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.536

High

756359

MCM7
DNA replication licensing factor MCM7

2

13

High-throughput

0.521

High

1200207

SWAHC
Ankyrin repeat domain-containing protein SOWAHC

1

16

High-throughput

0.514

High

344024

HS74L
Heat shock 70 kDa protein 4L

1

9

High-throughput

0.479

High

476196

ANXA5
Annexin A5

1

3

High-throughput

0.479

High

643565

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

660170

COF1
Cofilin-1

1

2

High-throughput

0.479

High

731631

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.479

High

773647

COPB2
Coatomer subunit beta'

1

3

High-throughput

0.479

High

921794

COPB
Coatomer subunit beta

1

6

High-throughput

0.479

High

934172

XPO2
Exportin-2

1

7

High-throughput

0.479

High

937349

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

4

High-throughput

0.479

High

1130192

SMC1A
Structural maintenance of chromosomes protein 1A

1

5

High-throughput

0.479

High

1291225

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

9

High-throughput

0.479

High

1314705

SRRM1
Serine/arginine repetitive matrix protein 1

1

6

High-throughput

0.479

High

1360487

PSPC1
Paraspeckle component 1

1

8

High-throughput

0.479

High

1409950

DDX50
ATP-dependent RNA helicase DDX50

1

5

High-throughput

0.479

High

1438964

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1438971

RUVB1
RuvB-like 1

1

3

High-throughput

0.479

High

1438972

NOP58
Nucleolar protein 58

1

3

High-throughput

0.479

High

1438973

SRPRB
Signal recognition particle receptor subunit beta

1

9

High-throughput

0.479

High

1438974

COPG1
Coatomer subunit gamma-1

1

10

High-throughput

0.479

High

408170

TBB4A
Tubulin beta-4A chain

1

0

High-throughput

0.458

High

975506

PRS10
26S proteasome regulatory subunit 10B

1

0

High-throughput

0.458

High

1187082

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

301818

ANXA9
Annexin A9

1

4

High-throughput

0.457

High

652582

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

12

High-throughput

0.457

High

1398319

PRIC1
Prickle-like protein 1

1

5

High-throughput

0.445

High

1438969

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

High-throughput

0.445

High

784735

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

2

High-throughput

0.437

High

895656

SERPH
Serpin H1

1

2

High-throughput

0.437

High

897983

CDK9
Cyclin-dependent kinase 9

1

6

High-throughput

0.437

High

1058670

CKAP4
Cytoskeleton-associated protein 4

1

14

High-throughput

0.437

High

1096233

TADBP
TAR DNA-binding protein 43

1

8

High-throughput

0.437

High

1109219

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

6

High-throughput

0.437

High

1210534

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

High-throughput

0.437

High

1351476

BRX1
Ribosome biogenesis protein BRX1 homolog

1

2

High-throughput

0.437

High

1399355

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

1

High-throughput

0.437

High

1407707

EBP2
Probable rRNA-processing protein EBP2

1

1

High-throughput

0.437

High

1429793

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.437

High

1438961

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

2

High-throughput

0.437

High

1438962

MIC19
MICOS complex subunit MIC19

1

4

High-throughput

0.437

High

1438963

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

1

High-throughput

0.437

High

1438965

STML2
Stomatin-like protein 2, mitochondrial

1

2

High-throughput

0.437

High

1403980

SCN2A
Sodium channel protein type 2 subunit alpha

1

2

High-throughput

0.417

High

325357

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

137823

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.249

Low

377730

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

469206

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.249

Low

1271150

TM10C
tRNA methyltransferase 10 homolog C

1

0

High-throughput

0.249

Low

1436939

SFXN1
Sideroflexin-1

1

0

High-throughput

0.249

Low

1438616

GLOD4
Glyoxalase domain-containing protein 4

1

0

High-throughput

0.249

Low

1438970

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.249

Low

1133361

NC2A
Dr1-associated corepressor

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025