HitPredict

Interactor 1: EVI5 (O60447)
Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein)
Gene: EVI5

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17229837
Identification Methods	surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 810 Hs			1 218
+	Hs
		248977 EVI5_HUMAN (1-810): 1.26e-107: 350: 100.00		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		976376 TBCD1_HUMAN (44-534): 2.82e-98: 332: 23.43		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Dm
		197387 EVI5_DROME (76-718): 3.13e-85: 290: 36.68		O18335_DROME (1-216): 1.86e-85: 253: 83.80
+	Hs
		1155376 EVI5L_HUMAN (50-712): 6.9e-76: 264: 68.93		RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00
+	Hs
		976478 EVI5L_HUMAN (50-712): 6.9e-76: 264: 68.93		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		247484 TBC12_HUMAN (13-431): 7.92e-70: 247: 21.53		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		1155398 TBC14_HUMAN (12-423): 1.12e-65: 234: 19.96		RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00
+	Hs
		976628 TBC14_HUMAN (12-423): 1.12e-65: 234: 19.96		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		247144 TBCD4_HUMAN (11-524): 2.71e-66: 242: 21.37		RAB2B_HUMAN (7-215): 1.34e-83: 249: 46.98
+	Hs
		956320 TB10B_HUMAN (31-450): 1.42e-83: 285: 20.14		RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56
+	Hs
		956351 TBCD9_HUMAN (3-487): 1.66e-68: 248: 19.88		RAB2A_HUMAN (8-178): 5.92e-61: 191: 55.56
+	Hs
		976687 RBGP1_HUMAN (558-808): 1.7e-10: 67: 13.04		RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37
+	Hs
		945127 RBGP1_HUMAN (558-808): 1.7e-10: 67: 13.04		RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63