Protein: GBA2
Non-lysosomal glucosylceramidase (NLGase) (EC 3.2.1.45) (Beta-glucocerebrosidase 2) (Beta-glucosidase 2) (Bile acid beta-glucosidase GBA2) (Bile acid glucosyl transferase GBA2) (Cholesterol glucosyltransferase GBA2) (EC 2.4.1.-) (Cholesteryl-beta-glucosidase GBA2) (EC 3.2.1.-) (Glucosylceramidase 2) (Non-lysosomal cholesterol glycosyltransferase) (Non-lysosomal galactosylceramidase) (EC 3.2.1.46) (Non-lysosomal glycosylceramidase)

Gene: GBA2
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q9HCG7

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004336 - galactosylceramidase activity
GO:0004348 - glucosylceramidase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005790 - smooth endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

50251

HACL2
2-hydroxyacyl-CoA lyase 2

3

0

High-throughput

0.646

High

206424

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.513

High

269543

SKAP2
Src kinase-associated phosphoprotein 2

1

0

High-throughput

0.513

High

560306

DPEP1
Dipeptidase 1

1

0

High-throughput

0.513

High

1025347

LIPA1
Liprin-alpha-1

1

0

High-throughput

0.513

High

1173720

VP13C
Intermembrane lipid transfer protein VPS13C

1

0

High-throughput

0.513

High

1334306

RM44
Large ribosomal subunit protein mL44

1

0

High-throughput

0.513

High

1336143

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

1336144

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

815928

MTR1A
Melatonin receptor type 1A

1

0

High-throughput

0.486

High

395818

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1240309

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

163991

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

839150

EMD
Emerin

1

0

High-throughput

0.458

High

890438

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

1313061

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1333575

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1336142

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

439090

ELNE
Neutrophil elastase

1

0

Small-scale

0.438

High

946978

RT22
Small ribosomal subunit protein mS22

1

1

High-throughput

0.437

High

103907

G5E9W7
Mitochondrial ribosomal protein S22

1

1

High-throughput

0.407

High

1240144

RDH13
Retinol dehydrogenase 13

1

0

High-throughput

0.279

Low

1336145

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.279

Low

575588

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

1171801

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1336141

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

517479

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024