HitPredict

Interactor 1: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Interactor 2: TBC14 (Q9P2M4)
TBC1 domain family member 14
Gene: TBC1D14

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	1.00	0.653

Property	Details
Experiments	22613832
Identification Methods	anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0055037 - recycling endosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 693
+	Hs
		976628 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		TBC14_HUMAN (1-693): 0: 729: 100.00
+	Hs
		247484 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		TBC12_HUMAN (220-690): 3.11e-122: 384: 68.64
+	Hs
		247144 RAB2B_HUMAN (7-215): 1.34e-83: 249: 46.98		TBCD4_HUMAN (90-684): 2.87e-107: 355: 17.14
+	Hs
		976376 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		TBCD1_HUMAN (161-692): 1.51e-94: 319: 15.86
+	Os
		823585 RIC2_ORYSJ (5-216): 2.35e-92: 271: 70.76		Q5SMT0_ORYSJ (231-661): 1.46e-91: 301: 16.56
+	Os
		1209948 Q84TA8_ORYSJ (7-217): 8.15e-92: 269: 42.93		Q5SMT0_ORYSJ (231-661): 1.46e-91: 301: 16.56
+	Dm
		197376 O18335_DROME (1-216): 1.86e-85: 253: 83.80		Q9VPL5_DROME (122-666): 7.07e-96: 313: 14.26
+	Hs
		976670 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		TBD2B_HUMAN (116-685): 5.47e-88: 297: 16.36
+	Dd
		356163 RB11A_DICDI (6-215): 8.44e-98: 285: 69.48		TBC12_DICDI (305-667): 5.58e-84: 273: 36.68
+	Hs
		1155376 RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00		EVI5L_HUMAN (289-692): 3.48e-83: 281: 20.68
+	Hs
		248986 RB11B_HUMAN (1-218): 6.92e-94: 275: 100.00		EVI5_HUMAN (321-692): 1.42e-82: 280: 20.84
+	Hs
		945050 RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63		TBC15_HUMAN (218-689): 9.49e-93: 304: 17.71
+	Hs
		976687 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		RBGP1_HUMAN (212-686): 2.85e-83: 286: 20.00
+	Hs
		945122 RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63		TBD2B_HUMAN (116-685): 5.47e-88: 297: 16.36
+	Hs
		976478 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		EVI5L_HUMAN (289-692): 3.48e-83: 281: 20.68
+	Hs
		248977 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		EVI5_HUMAN (321-692): 1.42e-82: 280: 20.84
+	Hs
		945127 RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63		RBGP1_HUMAN (212-686): 2.85e-83: 286: 20.00
+	Hs
		976596 RB11A_HUMAN (1-218): 3.63e-90: 265: 90.37		TB22B_HUMAN (224-663): 3.03e-80: 265: 16.60
+	Dm
		197387 O18335_DROME (1-216): 1.86e-85: 253: 83.80		EVI5_DROME (322-692): 6.19e-76: 262: 23.50
+	Hs
		945107 RAB25_HUMAN (2-218): 1.31e-83: 249: 60.63		TB22B_HUMAN (224-663): 3.03e-80: 265: 16.60