Interactor 1: DSCAM (O60469)
Cell adhesion molecule DSCAM (CHD2) (Down syndrome cell adhesion molecule)
Gene: DSCAM
Interactor 2: MERTK (Q12866)
Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)
Gene: MERTK
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35914814 |
| Identification Methods | two hybrid, two hybrid fragment pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | fn3~fn3, fn3~ig, Ig_3~fn3, PK_Tyr_Ser-Thr~fn3, I-set~fn3, I-set~ig, I-set~Ig_3, Ig_3~ig, Ig_3~Ig_3 |
| Common GO terms | GO:0005886 - plasma membrane GO:0007399 - nervous system development |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025